Table B1.
Hematocrit Change: Postheparinization to Nadir on CPB | |||
---|---|---|---|
β Estimate | 95% Confidence Interval | p-Value | |
Fixed effects | |||
Intercept | −7.777 | −8.04 to −7.52 | <.001 |
Cardioplegia type = MP* | .406 | .10 to .72 | .011 |
Cardioplegia type = DN* | −.281 | −.52 to −.04 | .022 |
Cardioplegia type = HTK* | −1.236 | −1.75 to −.72 | <.001 |
Net CPB circuit priming volume | −.128 | −.18 to −.08 | <.001 |
Perfusion volume added on CPB | −.728 | −.78 to −.67 | <.001 |
Urine output CPB | .0431 | −.01 to .10 | .109 |
Anesthesia volume added on CPB | −.181 | −.24 to −.13 | <.001 |
Ultrafiltration volume | .598 | .54 to .66 | <.001 |
Total CPB time | −.36 | −.47 to −.24 | <.001 |
Cross-clamp time | −.04 | −.15 to .07 | .476 |
Age | −.115 | −.16 to −.07 | <.001 |
Nadler total blood volume | 1.031 | .98 to 1.08 | <.001 |
Hct: first in O.R. | 1.054 | .96 to 1.14 | <.001 |
Hct: post-heparin | −3.667 | −3.76 to −3.57 | <.001 |
Female gender | −.586 | −.71 to −.47 | <.001 |
Diabetes | −.159 | −.25 to −.07 | <.001 |
Non-elective procedure | −.203 | −.32 to −.08 | <.001 |
Reoperation | −.163 | −.41 to .09 | .204 |
Aortic surgery† | .442 | .17 to .71 | .001 |
AV surgery + CABG† | .026 | −.15 to .20 | .772 |
Combined AV/MV surgery† | .890 | .53 to 1.25 | <.001 |
Isolated AV surgery† | .632 | .50 to .77 | <.001 |
Isolated MV surgery† | .795 | .61 to .98 | <.001 |
MV surgery + CAB† | .104 | −.16 to .37 | .443 |
Random effects | |||
Residual variance | 5.432 | ||
Variance attributable to surgeons | .204 | ||
Variance attributable to hospitals | 1.845 | ||
Number of surgeons | 434 | ||
Number of hospitals | 170 | ||
Intraclass correlation coefficient: surgeons | .027 | ||
Intraclass correlation coefficient: hospitals | .247 | ||
Observations | 13,434 |
All continuous variables have been scaled and centered before model estimation.
Effect defined relative to 4:1.
Effect defined relative to CABG procedure.