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. 2017 Aug 18;45(17):9860–9873. doi: 10.1093/nar/gkx714

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Volcano plot of genes found to be enriched in the SCN by meta-analysis. Plot shows enrichment in SCN versus WB (combined effect size, M*, derived from log₂-transformed fold changes) against the significance (FDR-corrected q-value), with error bars showing 95% confidence intervals. Genes with q < 0.01 and M* ≥3 shown in gold (426 highly enriched) and those with q < 0.01 and M* ≤−3 shown in blue (611 highly depleted). Genes labelled are the top enriched genes by combined effect size, or by significance, as well as the most depleted and most significant depleted genes.