Table 3. The enrichment of previously suggested SCN markers and genes important for signalling or rhythmicity, along with the combined effect size (M*) derived from the meta-analysis.
| MGI gene symbol | Effect size (M*) | Pubmed ID |
|---|---|---|
| Adcyap1 (PACAP) | 2.20 | 9065523 |
| Avp | 4.93 | 25741730 |
| Drd1a | −2.32 | 25643294 |
| Lhx1 | 2.52 | 21525287 |
| Nms | 3.86 | 15635449 |
| Prok2 | 3.19 | 12024206 |
| Rgs16 | 3.11 | 21610730 |
| Scg2 | 4.70 | 17319750 |
| Six3 | 3.85 | 21525287 |
| Six6 | 5.67 | 21525287 |
| Syt10 | 3.29 | 21921292 |
| Vip | 6.12 | 11207820 |
| Vipr2 | 2.48 | 12086606 |
Values in bold are those that meet the relevant cut-off (q-value < 0.01). Pubmed IDs provided for examples of the many references suggesting functional involvement in the SCN.