Table 3:

Identification of candidate camptothecin biosynthetic pathway genes in the Camptotheca acuminata genome as revealed by sequence identity and coverage with characterized genes from the 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate and iridoid biosynthetic pathways from Catharanthus roseus

Description	Abbreviation	Protein	Camptotheca gene ID	% coverage	% identity
MEP
1-deoxy-D-xylulose 5-phosphate synthase 2	DXS	ABI35993.1	Cac_g024944.t1	98	77.60
1-deoxy-D-xylulose-5-phosphate reductoisomerase	DXR	AAF65154.1	Cac_g016318.t1	100	88.82
4-diphosphocytidyl-methylerythritol 2-phosphate synthase	CMS	ACI16377.1	Cac_g018722.t1	88	77.82
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	CMK	ABI35992.1	Cac_g021688.t1	99	76.17
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	MCS	AAF65155.1	Cac_g008169.t1	100	73.77
GCPE protein	HDS	AAO24774.1	Cac_g022763.t1	100	88.65
1-hydroxy-2-methyl-butenyl 4-diphosphate reductase	HDR	ABI30631.1	Cac_g014659.t1	100	83.77
Plastid isopentenyl pyrophosphate: dimethylallyl pyrophosphate isomerase	IPI	ABW98669.1	Cac_g008847.t1	76	91.06
Geranyl pyrophosphate synthase	GPPS	ACC77966.1	Cac_g026508.t1	51	76.50
Iridoid
Geraniol 8-hydroxylase	G8H	CAC80883.1	Cac_g017987.t1	95	76.71
8-hydroxygeraniol oxidoreductase	GOR	AHK60836.1	Cac_g027560.t1	100	71.69
Iridoid synthase	ISY	AFW98981.1	Cac_g006027.t1	100	65.65
Iridoid oxidase	IO	AHK60833.1	Cac_g032709.t1	97	78.44
UDP-glucose iridoid glucosyltransferase	7DLGT	BAO01109.1	Cac_g008744.t1	100	77.11
7-deoxyloganic acid 7-hydroxylase	7DLH	AGX93062.1	Cac_g012663.t1	96	69.58
Loganic acid methyltransferase	LAMT	ABW38009.1	Cac_g005179.t1	95	53.91
Secologanin synthase	SLS	AAA33106.1	Cac_g012666.t1	99	64.94

Only the top hit from the BLAST search is presented.