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. 2017 Sep 7;45(19):11425–11436. doi: 10.1093/nar/gkx795

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — FosB/JunD in the DNA-free form. (A) FosB/JunD dimer in FJ^oxi (type I). Leucines at the d-positions are shown. (B) Dimer interface of FJ^oxi type I (left) and FJ crystal (right) structures showing Heptad -1 to Heptad 2. Key hydrogen bonds in dashed lines. (C) Composite omit electron density map around the FosB/JunD C¹⁷²/C²⁸⁵ disulfide bond (contoured at 1.0 σ) in the fully oxidized FJ^oxi type I (left) and partially oxidized FJ (right) heterodimer. Relevant side chains (C¹⁷², C²⁸⁵), backbone atoms (R²⁸⁶, A²⁸²) and distances, as discussed in the text. (D) Adapted helical wheel of the interface between FosB (orange, purple)/JunD (cyan) depicting the a/d/g-residues of the heptad repeat preceding and following the kink in FosB. (E) Schematic representation of FosB, JunD and GCN4 monomers in the DNA-free form. Bars represent helices; thin bars, kinks; dots, disordered peptide. Color scheme is indicated in (A) and applies to all sub-figures. Non-carbon atoms are colored as in Figure 1.