Table 1. The names, localization and functions of the FASTK family proteins.
| Subcellular localization | RNAs regulated | Mitochondrial function | |
|---|---|---|---|
| FASTK | Nucleus, cytosol and mitochondria (MRGs) | MT-ND6 | MT-ND6 3′ end generation and stability |
| FASTKD1 | Mitochondria (nucleoids and MRGs) | MT-ND3 | mRNA stability |
| FASTKD2 | Mitochondria (MRGs) | MT-RNR2 (16S rRNA), MT-ND6 | rRNA/mRNA stability |
| FASTKD3 | Mitochondria | MT-ND2, MT-ND3, MT-ATP8/6, MT-CYB, MT-CO2 | mRNA stability, MT-CO1 translation |
| FASTKD4 | Mitochondria | MT-ND3, MT-ND5, MT-CYB, MT-CO1, MT-CO2, MT-CO3, MT-ATP8/6 | mRNA stability and processing |
| FASTKD5 | Mitochondria (MRGs) | All MT-mRNAs | mRNA processing |