TABLE 3.
Treatment characteristics and local progression*
| Characteristic | Total | Local Progression
|
|
|---|---|---|---|
| Yes | No | ||
| preop RT failure† | 91 | 21 (23.1) | 57 (62.6) |
| cEBRT | 58 | 15 (25.9) | 32(55.2) |
| hypofractionated SRS | 18 | 4 (22.2) | 14 (77.8) |
| single-fraction SRS | 7 | 1 (14.3) | 6 (85.7) |
| surgical decompression | |||
| age at surgery (yrs) | |||
| median | 58.9 | 61.5 | 57.9 |
| range | 14.8–81.4 | 16.2–79.4 | 14.8–81.4 |
| no. of spinal levels | |||
| median | 2 | 3 | 2 |
| range | 1–8 | 1–8 | 1–6 |
| time to RT (mos) | |||
| median | 1.6 | 1.5 | 1.8 |
| range | 0.4–46.1 | 0.6–20.3 | 0.4–46.1 |
| postop ESCC | |||
| no compression (0, 1a) | 67 | 10 (14.9) | 50 (74.6) |
| dural compression (1b, 1c) | 98 | 19 (19.4) | 71 (72.4) |
| cord compression (2, 3) | 21 | 5 (23.8) | 10 (47.6) |
| postop adjuvant SRS | |||
| low-dose hypo | 109 | 28 (23.5) | 65 (54.6) |
| high-dose hypo | 37 | 1 (2–7) | 34(91.9) |
| single-fraction | 40 | 5(12.5) | 32 (80.0) |
| no. of spinal levels | |||
| median | 2 | 2 | 3 |
| range | 1–11 | 1–8 | 1–11 |
*
Values in data cells represent numbers of cases (%) unless otherwise indicated Abbreviation: hypo = hypofractionated.
†
The fractionation scheme of preoperative radiation was unknown in 8 patients.