Table 4.

Sensitivity analysis for base case, low-resource and high-resource country scenarios

	ICER	ICER	ICER
	Base case	Low resource	High resource
Tested rate
20	93.58	78.85	114.95
40	93.63	78.89	115.02
51 (base case)	93.62	78.88	115.05
60	93.62	78.90	115.05
80	93.61	78.89	115.06
Treated rate
16 (base case)	93.62	78.88	115.05
20	76.10	64.12	93.52
40	41.04	34.60	50.42
60	29.36	24.76	36.06
80	23.52	19.84	28.87
Device sensitivity, Microlife
70	119.59	100.77	146.99
80	105.49	88.90	129.71
90	94.57	79.71	116.21
91 (base case)	93.62	78.88	115.05
95	89.95	75.81	110.55
99	86.62	72.99	106.47
99.5	86.22	72.67	105.96
Device sensitivity, Uristik
68 (base case)	93.62	78.88	115.05
70	91.10	76.79	111.99
80	80.47	67.83	98.89
90	72.18	60.84	88.74
95	68.70	57.91	84.43
99	66.17	55.78	81.33
99.5	65.88	55.52	80.94
Device specificity, Microlife
70	278.55	234.62	342.39
80	188.34	158.65	231.49
90	98.13	82.68	120.60
90.5 (base case)	93.62	78.88	115.05
95	53.03	44.69	65.15
99	16.95	14.30	20.63
99.5	12.44	10.50	15.25
Device specificity, Uristik
68 (base case)	93.62	78.88	115.05
70	88.51	74.57	108.77
80	62.96	53.05	77.36
90	37.41	31.54	45.95
95	24.63	20.78	30.24
99	14.41	12.17	17.68
99.5	13.14	11.09	16.10
Discount rate
0%	0.02	0.02	0.02
3% (base case)	93.62	78.88	115.05
6%	−0.03	−0.03	−0.03
Life expectancy
55 (base case)	93.62	78.88	115.05
65	0.07	0.07	0.07
HRQL
0.2	167.40	123.91	257.45
0.25 (base case)	93.62	78.88	115.05
0.3	64.98	57.87	74.08

Notes: Table reports simulation results of ICERs from varying the mean of each parameter as indicated for Microlife/Uristik device combination. Each cell represents a separate simulation. Low-resource country scenario (e.g., Nigeria) has high general mortality: untreated survival 92.4%; treated survival 98.93%. High-resource country scenario (e.g., South Africa) has low general mortality: untreated survival 96.4%; treated survival 99.93%.