TABLE.
Characteristic | Aspirin n = 221 |
Placebo n = 223 |
P | Vascular n = 53 |
Nonvascular n = 391 |
P |
---|---|---|---|---|---|---|
Parous | 107 (48.4) | 114 (51.1) | .569 | 15 (28.3) | 206 (52.7) | <.001 |
Age, y | ||||||
<35 | 204 (92.7) | 197 (88.3) | .115 | 50 (94.3) | 351 (90.0) | .312 |
≥35 | 16 (7.3) | 26 (11.7) | 3 (5.7) | 39 (10.0) | ||
Body mass index | ||||||
Underweight | 3 (1.4) | 3 (1.4) | .712 | 1 (1.9) | 5 (1.3) | .672 |
Normal | 103 (46.8) | 95 (43.2) | 25 (47.2) | 173 (44.7) | ||
Overweight | 44 (20.0) | 54 (24.6) | 14 (26.4) | 84 (21.7) | ||
Obese | 70 (31.8) | 68 (30.9) | 13 (24.5) | 125 (32.3) | ||
Black race | 89 (40.2) | 86 (38.6) | .713 | 13 (24.5) | 162 (41.4) | .018 |
Education ≤12 y | 130 (58.8) | 144 (64.6) | .213 | 29 (54.7) | 245 (62.7) | .264 |
Gestational age, wk, at randomization, mean (SD) | 18.5 (0.3) | 18.1 (0.3) | .329 | 18.4 (0.6) | 18.3 (0.2) | .878 |
Chronic hypertension | 21 (9.5) | 30 (13.5) | .192 | 16 (30.2) | 35 (9.0) | <.001 |
Cigarette smoking | ||||||
Never | 155 (70.1) | 150 (67.6) | .626 | 39 (73.6) | 266 (68.2) | .564 |
Quit during pregnancy | 18 (8.1) | 24 (10.8) | 3 (5.7) | 39 (10.0) | ||
Yes, current | 48 (21.7) | 48 (21.6) | 11 (20.8) | 85 (21.8) | ||
White classification | ||||||
B | 78 (35.3) | 74 (33.2) | .783 | 0 (0.0) | 152 (38.9) | |
C | 94 (42.5) | 92 (41.3) | 0 (0.0) | 186 (47.6) | ||
D | 27 (12.2) | 26 (11.7) | 0 (0.0) | 53 (13.6) | ||
F | 15 (6.8) | 20 (9.0) | 35 (66.0) | 0 (0.0) | ||
R | 7 (3.2) | 11 (4.9) | 18 (34.0) | 0 (0.0) |
Values are n (%) unless otherwise noted.
Adkins et al. Aspirin and fetal growth in diabetic pregnancies. Am J Obstet Gynecol 2017.