Table 1. Chemical structures and anti-inflammatory and anti-amyloid aggregation activity of synthetic curcumin derivatives.

Compound Structure		aIC50±S.D (μM)	bThT assay IC50 (μM)
2		2.23±0.84	NA
3		1.81±1.31	2.05±0.1
4		2.21±0.93	1.32±0.7
5		14.2±12.8	1.96±0.7
6		2.50±0.92	1.77±0.9
8		8.28±3.08	NA
10		3.22±1.34	2.04±0.7
1		8.25±1.25	1.49±0.9

^a,bValues represent average of IC₅₀ from three independent experiments performed in duplicate±S.D.