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. Author manuscript; available in PMC: 2017 Dec 20.
Published in final edited form as: J Phys Chem C Nanomater Interfaces. 2017 Aug 22;121(36):20007–20015. doi: 10.1021/acs.jpcc.7b05169

Figure 4.

Figure 4

Aβ40 aggregation kinetics in the presence of AuNPs. (a) Aβ40 (10 μM) aggregation kinetics in the absence or presence of AuNPs followed by ThT fluorescence (pH 7.4, 37°C). (b) UV-Vis spectra of AuNPs in the absence or presence of different amount of Aβ40 monomers in pH 7.4 phosphate buffer measured at 0 h. The spectra were normalized by setting the maximum intensity of the SPR band of the AuNP only sample to 1. (c) UV-Vis spectra of AuNPs measured after 24 h incubation. The spectra were normalized by setting the maximum intensity of the SPR band of the AuNP only sample to 1. (d) Aβ40 aggregation kinetics followed by the SPR band intensity change at 535 nm. The values of the band intensity change were calculated by subtracting the UV-Vis spectrum of AuNP only sample from those of AuNP‒Aβ40 mixtures measured at each time point.