Table 1.
Counts and age-adjusted incidence ratesa of malignant brain and other CNS tumors by region, site, and age group (CBTRUS and CI5-X, 2003–2007)
| Site and Region | All Ages | Children (0–14) | AYA (15–39) | Older Adults (40+) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Count | AAAIR | 95% CI | Count | AAAIR | 95% CI | Count | AAAIR | 95% CI | Count | AAAIR | 95% CI | |
| Brain | ||||||||||||
| Global | 264 241 | 5.57 | 5.55–5.60 | 19 852 | 2.28 | 2.25–2.32 | 39 494 | 2.35 | 2.33–2.37 | 204 895 | 11.75 | 11.69–11.80 |
| Australia and New Zealand | 8272 | 6.38 | 6.24–6.53 | 453 | 1.88 | 1.71–2.06 | 1131 | 2.57 | 2.42–2.72 | 6688 | 14.15 | 13.81–14.5 |
| Canada | 11 386 | 6.53 | 6.41–6.66 | 758 | 2.70 | 2.51–2.90 | 1478 | 2.61 | 2.47–2.74 | 9150 | 13.91 | 13.62–14.2 |
| East Asia | 16 279 | 3.07 | 3.02–3.12 | 1469 | 1.77 | 1.68–1.87 | 3008 | 1.49 | 1.43–1.54 | 11 802 | 5.86 | 5.75–5.97 |
| Eastern Europe and Central Asia | 25 761 | 4.82 | 4.76–4.89 | 1508 | 2.25 | 2.13–2.36 | 4266 | 2.51 | 2.43–2.58 | 19 987 | 9.42 | 9.29–9.55 |
| India | 5578 | 2.85 | 2.78–2.93 | 770 | 1.17 | 1.09–1.26 | 1670 | 1.51 | 1.43–1.58 | 3138 | 5.67 | 5.47–5.88 |
| Latin America | 6979 | 4.87 | 4.75–4.99 | 869 | 1.95 | 1.82–2.09 | 1429 | 1.96 | 1.86–2.07 | 4681 | 10.40 | 10.09–10.71 |
| Middle East and North Africa | 5587 | 4.21 | 4.09–4.32 | 768 | 1.77 | 1.64–1.90 | 1148 | 1.73 | 1.64–1.84 | 3671 | 8.88 | 8.59–9.17 |
| Northern Europe | 36 941 | 6.59 | 6.52–6.66 | 1794 | 2.11 | 2.01–2.21 | 4593 | 2.73 | 2.65–2.81 | 30 554 | 14.40 | 14.23–14.56 |
| Southeast Asia | 2686 | 2.55 | 2.44–2.66 | 478 | 1.42 | 1.30–1.55 | 668 | 1.13 | 1.05–1.22 | 1540 | 5.02 | 4.75–5.30 |
| Southeast Africa | 125 | 0.71 | 0.57–0.88 | 45 | 0.46 | 0.33–0.61 | 38 | 0.34 | 0.23–0.47 | 42 | 1.34 | 0.96–1.82 |
| Southern Europe | 19 443 | 6.89 | 6.78–6.99 | 751 | 2.37 | 2.20–2.54 | 2156 | 2.73 | 2.61–2.85 | 16 536 | 15.06 | 14.83–15.29 |
| United States | 101 243 | 5.74 | 5.71–5.78 | 9116 | 3.03 | 2.97–3.09 | 14 959 | 2.88 | 2.84–2.93 | 77 168 | 11.06 | 10.98–11.14 |
| Western Europe | 23 961 | 5.84 | 5.77–5.92 | 1073 | 2.00 | 1.88–2.13 | 2950 | 2.53 | 2.44–2.62 | 19 938 | 12.54 | 12.36–12.72 |
| Other parts of central nervous system | ||||||||||||
| Global | 12 542 | 0.28 | 0.28–0.29 | 2371 | 0.28 | 0.27–0.29 | 2689 | 0.16 | 0.15–0.17 | 7482 | 0.42 | 0.41–0.43 |
| Australia and New Zealand | 257 | 0.22 | 0.19–0.25 | 57 | 0.24 | 0.18–0.31 | 59 | 0.14 | 0.10–0.18 | 141 | 0.29 | 0.24–0.34 |
| Canada | 384 | 0.25 | 0.23–0.28 | 91 | 0.33 | 0.27–0.41 | 93 | 0.16 | 0.13–0.20 | 200 | 0.29 | 0.25–0.33 |
| East Asia | 1237 | 0.22 | 0.21–0.24 | 95 | 0.12 | 0.10–0.15 | 292 | 0.14 | 0.13–0.16 | 850 | 0.39 | 0.37–0.42 |
| Eastern Europe and Central Asia | 933 | 0.19 | 0.18–0.20 | 104 | 0.16 | 0.13–0.19 | 215 | 0.13 | 0.11–0.14 | 614 | 0.29 | 0.27–0.32 |
| India | 96 | 0.05 | 0.04–0.06 | 20 | 0.03 | 0.02–0.05 | 27 | 0.02 | 0.02–0.04 | 49 | 0.09 | 0.07–0.12 |
| Latin America | 307 | 0.21 | 0.19–0.24 | 56 | 0.13 | 0.10–0.16 | 71 | 0.10 | 0.08–0.12 | 180 | 0.41 | 0.35–0.47 |
| Middle East and North Africa | 248 | 0.17 | 0.15–0.19 | 72 | 0.17 | 0.13–0.21 | 82 | 0.12 | 0.10–0.15 | 94 | 0.22 | 0.18–0.27 |
| Northern Europe | 1952 | 0.39 | 0.37–0.41 | 272 | 0.32 | 0.28–0.36 | 376 | 0.22 | 0.20–0.25 | 1304 | 0.63 | 0.59–0.66 |
| Southeast Asia | 57 | 0.05 | 0.04–0.07 | – | – | – | 19 | 0.03 | 0.02–0.05 | 34 | 0.10 | 0.07–0.15 |
| Southeast Africa | – | – | – | – | – | – | – | – | – | – | – | – |
| Southern Europe | 631 | 0.26 | 0.24–0.28 | 74 | 0.23 | 0.18–0.29 | 115 | 0.15 | 0.12–0.18 | 442 | 0.42 | 0.38–0.46 |
| United States | 5703 | 0.37 | 0.36–0.38 | 1380 | 0.46 | 0.44–0.49 | 1184 | 0.23 | 0.22–0.24 | 3139 | 0.47 | 0.46–0.49 |
| Western Europe | 728 | 0.22 | 0.20–0.24 | 146 | 0.28 | 0.23–0.32 | 152 | 0.13 | 0.11–0.16 | 430 | 0.28 | 0.25–0.30 |
| Meninges | ||||||||||||
| Global | 10 321 | 0.21 | 0.21–0.22 | 177 | 0.02 | 0.02–0.02 | 1014 | 0.06 | 0.06–0.06 | 9130 | 0.53 | 0.52–0.54 |
| Australia and New Zealand | 177 | 0.13 | 0.11–0.16 | – | – | – | 21 | 0.05 | 0.03–0.07 | 156 | 0.34 | 0.28–0.39 |
| Canada | 335 | 0.19 | 0.17–0.21 | – | – | – | 35 | 0.06 | 0.04–0.08 | 295 | 0.47 | 0.41–0.52 |
| East Asia | 2248 | 0.40 | 0.38–0.42 | 21 | 0.03 | 0.02–0.04 | 150 | 0.07 | 0.06–0.08 | 2077 | 1.05 | 1.01–1.10 |
| Eastern Europe and Central Asia | 1617 | 0.28 | 0.27–0.30 | 17 | 0.03 | 0.01–0.04 | 194 | 0.11 | 0.10–0.13 | 1406 | 0.67 | 0.64–0.71 |
| India | 102 | 0.06 | 0.05–0.08 | – | – | – | 18 | 0.02 | 0.01–0.03 | 81 | 0.16 | 0.12–0.20 |
| Latin America | 419 | 0.29 | 0.27–0.33 | 54 | 0.12 | 0.09–0.16 | 76 | 0.10 | 0.08–0.13 | 289 | 0.64 | 0.57–0.72 |
| Middle East and North Africa | 162 | 0.13 | 0.11–0.15 | – | – | – | 15 | 0.02 | 0.01–0.04 | 141 | 0.34 | 0.29–0.40 |
| Northern Europe | 768 | 0.13 | 0.13–0.15 | – | – | – | 86 | 0.05 | 0.04–0.06 | 674 | 0.33 | 0.30–0.35 |
| Southeast Asia | 103 | 0.10 | 0.08–0.13 | – | – | – | 16 | 0.03 | 0.02–0.04 | 86 | 0.27 | 0.21–0.33 |
| Southeast Africa | 15 | 0.13 | 0.07–0.21 | – | – | – | – | – | – | – | – | – |
| Southern Europe | 982 | 0.33 | 0.31–0.35 | – | – | – | 78 | 0.09 | 0.07–0.12 | 894 | 0.82 | 0.77–0.88 |
| United States | 2630 | 0.13 | 0.13–0.14 | 44 | 0.01 | 0.01–0.02 | 258 | 0.05 | 0.04–0.06 | 2328 | 0.32 | 0.31–0.33 |
| Western Europe | 763 | 0.18 | 0.17–0.19 | – | – | – | 63 | 0.05 | 0.04–0.07 | 693 | 0.45 | 0.42–0.49 |
–Categories with fewer than 16 cases were suppressed.
aRates are per 100000 persons and are age adjusted to the World Health Organization Standard Million.
Abbreviations: AAAIR: average annual age adjusted incidence rate; AYA: adolescents and young adults ages 15–39.