Table 2.
Counts and age-adjusted incidence ratesa of malignant brain and other CNS tumors by region, histology, and age group (CBTRUS and CI5-X, 2003–2007)
| Histology and Region | All Ages | Children (0–14) | AYA (15–39) | Older Adults (40+) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Count | AAAIR | 95% CI | Count | AAAIR | 95% CI | Count | AAAIR | 95% CI | Count | AAAIR | 95% CI | |
| Astrocytic tumors | ||||||||||||
| Global | 146 621 | 2.98 | 2.97–3.00 | 6595 | 0.75 | 0.73–0.77 | 19 277 | 1.14 | 1.13–1.16 | 120 749 | 6.77 | 6.73–6.81 |
| Australia and New Zealand | 5363 | 3.94 | 3.83–4.05 | 92 | 0.38 | 0.31–0.46 | 606 | 1.36 | 1.26–1.48 | 4665 | 9.58 | 9.30–9.86 |
| Canada | 6603 | 3.58 | 3.49–3.67 | 313 | 1.10 | 0.98–1.23 | 637 | 1.13 | 1.04–1.22 | 5653 | 8.26 | 8.04–8.48 |
| East Asia | 5539 | 0.96 | 0.93–0.99 | 259 | 0.30 | 0.26–0.34 | 1127 | 0.54 | 0.51–0.58 | 4153 | 1.93 | 1.87–1.99 |
| Eastern Europe and Central Asia | 12 018 | 2.21 | 2.17–2.25 | 481 | 0.70 | 0.64–0.77 | 2260 | 1.33 | 1.27–1.38 | 9277 | 4.37 | 4.28–4.46 |
| India | 2833 | 1.50 | 1.45–1.56 | 176 | 0.26 | 0.22–0.30 | 845 | 0.76 | 0.71–0.81 | 1812 | 3.29 | 3.14–3.45 |
| Latin America | 3070 | 2.09 | 2.01–2.16 | 215 | 0.48 | 0.42–0.55 | 647 | 0.89 | 0.82–0.96 | 2208 | 4.67 | 4.47–4.87 |
| Middle East and North Africa | 3096 | 2.39 | 2.31–2.48 | 234 | 0.54 | 0.47–0.61 | 544 | 0.83 | 0.76–0.90 | 2318 | 5.59 | 5.36–5.82 |
| Northern Europe | 17 477 | 2.98 | 2.94–3.03 | 501 | 0.58 | 0.53–0.64 | 2326 | 1.38 | 1.32–1.43 | 14 650 | 6.63 | 6.53–6.74 |
| Southeast Asia | 996 | 0.93 | 0.87–0.99 | 101 | 0.30 | 0.25–0.37 | 288 | 0.49 | 0.43–0.55 | 607 | 1.91 | 1.75–2.08 |
| Southeast Africa | 22 | 0.13 | 0.07–0.21 | – | – | – | – | – | – | – | – | – |
| Southern Europe | 8822 | 3.01 | 2.95–3.08 | 199 | 0.63 | 0.54–0.72 | 986 | 1.22 | 1.15–1.30 | 7637 | 6.86 | 6.71–7.02 |
| United States | 65 305 | 3.59 | 3.56–3.62 | 3754 | 1.24 | 1.20–1.28 | 7405 | 1.43 | 1.39–1.46 | 54 146 | 7.83 | 7.77–7.90 |
| Western Europe | 15 642 | 3.59 | 3.53–3.65 | 274 | 0.50 | 0.45–0.57 | 1620 | 1.38 | 1.31–1.45 | 13 748 | 8.45 | 8.30–8.59 |
| Oligodendroglial tumors and mixed gliomas | ||||||||||||
| Global | 20 676 | 0.43 | 0.42–0.43 | 547 | 0.06 | 0.06–0.07 | 7118 | 0.42 | 0.41–0.43 | 13 011 | 0.71 | 0.70–0.73 |
| Australia and New Zealand | 849 | 0.64 | 0.60–0.69 | 16 | 0.07 | 0.04–0.11 | 255 | 0.57 | 0.50–0.65 | 578 | 1.17 | 1.07–1.27 |
| Canada | 1226 | 0.67 | 0.64–0.71 | – | – | – | 400 | 0.69 | 0.62–0.76 | 815 | 1.14 | 1.06–1.22 |
| East Asia | 1174 | 0.20 | 0.19–0.21 | 28 | 0.03 | 0.02–0.05 | 416 | 0.19 | 0.18–0.21 | 730 | 0.33 | 0.30–0.35 |
| Eastern Europe and Central Asia | 1365 | 0.26 | 0.25–0.28 | 43 | 0.06 | 0.04–0.08 | 403 | 0.24 | 0.21–0.26 | 919 | 0.44 | 0.41–0.47 |
| India | 388 | 0.18 | 0.16–0.20 | 21 | 0.03 | 0.02–0.05 | 171 | 0.16 | 0.13–0.18 | 196 | 0.31 | 0.27–0.36 |
| Latin America | 465 | 0.29 | 0.27–0.32 | 18 | 0.04 | 0.02–0.06 | 172 | 0.24 | 0.20–0.28 | 275 | 0.55 | 0.49–0.62 |
| Middle East and North Africa | 439 | 0.31 | 0.28–0.34 | 21 | 0.05 | 0.03–0.07 | 177 | 0.27 | 0.23–0.31 | 241 | 0.55 | 0.49–0.63 |
| Northern Europe | 2425 | 0.45 | 0.44–0.47 | 57 | 0.07 | 0.05–0.09 | 717 | 0.42 | 0.39–0.45 | 1651 | 0.79 | 0.75–0.83 |
| Southeast Asia | 132 | 0.11 | 0.09–0.14 | – | – | – | 51 | 0.09 | 0.06–0.11 | 73 | 0.22 | 0.17–0.28 |
| Southeast Africa | – | – | – | – | – | – | – | – | – | – | – | – |
| Southern Europe | 965 | 0.37 | 0.34–0.39 | – | – | – | 303 | 0.36 | 0.32–0.40 | 648 | 0.62 | 0.57–0.67 |
| United States | 8922 | 0.56 | 0.55–0.57 | 253 | 0.08 | 0.07–0.09 | 3384 | 0.65 | 0.62–0.67 | 5285 | 0.83 | 0.80–0.85 |
| Western Europe | 2365 | 0.61 | 0.59–0.64 | 55 | 0.10 | 0.08–0.13 | 685 | 0.57 | 0.53–0.62 | 1625 | 1.04 | 0.99–1.09 |
| Ependymal tumors | ||||||||||||
| Global | 8565 | 0.19 | 0.19–0.20 | 1838 | 0.21 | 0.20–0.22 | 2411 | 0.14 | 0.14–0.15 | 4316 | 0.24 | 0.23–0.24 |
| Australia and New Zealand | 275 | 0.23 | 0.20–0.26 | 52 | 0.22 | 0.16–0.29 | 75 | 0.18 | 0.14–0.22 | 148 | 0.30 | 0.25–0.35 |
| Canada | 326 | 0.21 | 0.19–0.23 | 64 | 0.23 | 0.18–0.30 | 97 | 0.17 | 0.14–0.21 | 165 | 0.23 | 0.20–0.27 |
| East Asia | 569 | 0.12 | 0.11–0.13 | 125 | 0.16 | 0.14–0.20 | 170 | 0.08 | 0.07–0.10 | 274 | 0.12 | 0.11–0.14 |
| Eastern Europe and Central Asia | 602 | 0.14 | 0.13–0.16 | 133 | 0.20 | 0.17–0.24 | 189 | 0.11 | 0.10–0.13 | 280 | 0.13 | 0.12–0.15 |
| India | 158 | 0.07 | 0.06–0.08 | 50 | 0.08 | 0.06–0.10 | 53 | 0.05 | 0.04–0.06 | 55 | 0.09 | 0.07–0.12 |
| Latin America | 214 | 0.13 | 0.11–0.15 | 94 | 0.21 | 0.17–0.26 | 68 | 0.09 | 0.07–0.12 | 52 | 0.10 | 0.08–0.14 |
| Middle East and North Africa | 245 | 0.16 | 0.14–0.18 | 83 | 0.19 | 0.15–0.24 | 82 | 0.12 | 0.10–0.15 | 80 | 0.19 | 0.15–0.23 |
| Northern Europe | 1027 | 0.22 | 0.20–0.23 | 208 | 0.25 | 0.21–0.28 | 254 | 0.16 | 0.14–0.18 | 565 | 0.27 | 0.25–0.29 |
| Southeast Asia | 51 | 0.04 | 0.03–0.05 | 19 | 0.06 | 0.03–0.09 | 20 | 0.03 | 0.02–0.05 | – | – | – |
| Southeast Africa | – | – | – | – | – | – | – | – | – | – | – | – |
| Southern Europe | 432 | 0.20 | 0.18–0.22 | 72 | 0.23 | 0.18–0.29 | 120 | 0.16 | 0.13–0.19 | 240 | 0.23 | 0.20–0.26 |
| United States | 3886 | 0.26 | 0.25–0.27 | 794 | 0.27 | 0.25–0.28 | 1080 | 0.21 | 0.20–0.22 | 2012 | 0.31 | 0.30–0.33 |
| Western Europe | 776 | 0.23 | 0.22–0.25 | 141 | 0.26 | 0.22–0.31 | 202 | 0.18 | 0.15–0.2 | 433 | 0.28 | 0.25–0.31 |
| Medulloblastoma | ||||||||||||
| Global | 5933 | 0.16 | 0.16–0.17 | 3842 | 0.44 | 0.43–0.46 | 1660 | 0.10 | 0.10–0.11 | 431 | 0.02 | 0.02–0.03 |
| Australia and New Zealand | 172 | 0.18 | 0.15–0.20 | 111 | 0.46 | 0.38–0.56 | 48 | 0.12 | 0.08–0.15 | – | – | – |
| Canada | 197 | 0.16 | 0.14–0.18 | 114 | 0.41 | 0.34–0.49 | 51 | 0.09 | 0.07–0.12 | 32 | 0.04 | 0.03–0.06 |
| East Asia | 421 | 0.12 | 0.11–0.14 | 314 | 0.38 | 0.34–0.43 | 94 | 0.05 | 0.04–0.07 | – | – | – |
| Eastern Europe and Central Asia | 594 | 0.19 | 0.17–0.21 | 340 | 0.51 | 0.46–0.57 | 181 | 0.11 | 0.09–0.12 | 73 | 0.04 | 0.03–0.05 |
| India | 271 | 0.11 | 0.09–0.12 | 196 | 0.30 | 0.26–0.35 | 66 | 0.06 | 0.04–0.07 | – | – | – |
| Latin America | 333 | 0.19 | 0.17–0.21 | 220 | 0.49 | 0.43–0.56 | 95 | 0.13 | 0.10–0.16 | 18 | 0.03 | 0.02–0.05 |
| Middle East and North Africa | 279 | 0.17 | 0.15–0.19 | 180 | 0.41 | 0.36–0.48 | 81 | 0.12 | 0.10–0.15 | 18 | 0.04 | 0.02–0.06 |
| Northern Europe | 571 | 0.16 | 0.15–0.18 | 383 | 0.45 | 0.41–0.50 | 149 | 0.09 | 0.08–0.11 | 39 | 0.02 | 0.01–0.03 |
| Southeast Asia | 146 | 0.11 | 0.10–0.13 | 118 | 0.35 | 0.29–0.42 | 16 | 0.03 | 0.02–0.04 | – | – | – |
| Southeast Africa | – | – | – | – | – | – | – | – | – | – | – | – |
| Southern Europe | 314 | 0.22 | 0.20–0.25 | 182 | 0.58 | 0.50–0.67 | 111 | 0.16 | 0.13–0.19 | 21 | 0.02 | 0.01–0.03 |
| United States | 2210 | 0.18 | 0.17–0.19 | 1422 | 0.48 | 0.45–0.5 | 636 | 0.13 | 0.12–0.14 | 152 | 0.02 | 0.02–0.03 |
| Western Europe | 421 | 0.18 | 0.17–0.20 | 258 | 0.48 | 0.42–0.54 | 132 | 0.13 | 0.11–0.15 | 31 | 0.02 | 0.01–0.03 |
| Other embryonal tumors | ||||||||||||
| Global | 3121 | 0.09 | 0.08–0.09 | 1856 | 0.22 | 0.21–0.23 | 715 | 0.04 | 0.04–0.05 | 550 | 0.03 | 0.03–0.03 |
| Australia and New Zealand | 101 | 0.10 | 0.08–0.13 | 67 | 0.28 | 0.22–0.36 | 22 | 0.05 | 0.03–0.08 | – | – | – |
| Canada | 122 | 0.10 | 0.08–0.12 | 69 | 0.25 | 0.20–0.32 | 30 | 0.05 | 0.04–0.08 | 23 | 0.03 | 0.02–0.05 |
| East Asia | 255 | 0.07 | 0.06–0.08 | 135 | 0.18 | 0.15–0.21 | 64 | 0.03 | 0.03–0.04 | 56 | 0.03 | 0.02–0.04 |
| Eastern Europe and Central Asia | 192 | 0.06 | 0.05–0.07 | 87 | 0.14 | 0.11–0.17 | 51 | 0.03 | 0.02–0.04 | 54 | 0.03 | 0.02–0.03 |
| India | 108 | 0.05 | 0.04–0.06 | 62 | 0.10 | 0.08–0.13 | 30 | 0.03 | 0.02–0.04 | 16 | 0.03 | 0.02–0.05 |
| Latin America | 120 | 0.07 | 0.06–0.09 | 66 | 0.15 | 0.12–0.19 | 38 | 0.05 | 0.04–0.07 | 16 | 0.04 | 0.02–0.06 |
| Middle East and North Africa | 127 | 0.08 | 0.07–0.09 | 75 | 0.17 | 0.14–0.22 | 35 | 0.05 | 0.04–0.07 | 17 | 0.04 | 0.02–0.06 |
| Northern Europe | 330 | 0.09 | 0.08–0.10 | 168 | 0.20 | 0.17–0.23 | 87 | 0.05 | 0.04–0.07 | 75 | 0.04 | 0.03–0.04 |
| Southeast Asia | 55 | 0.04 | 0.03–0.06 | 35 | 0.10 | 0.07–0.14 | – | – | – | – | – | – |
| Southeast Africa | – | – | – | – | – | – | – | – | – | – | – | – |
| Southern Europe | 155 | 0.09 | 0.08–0.11 | 64 | 0.20 | 0.16–0.26 | 42 | 0.06 | 0.04–0.08 | 49 | 0.05 | 0.03–0.06 |
| United States | 1341 | 0.11 | 0.10–0.12 | 914 | 0.31 | 0.29–0.33 | 248 | 0.05 | 0.04–0.06 | 179 | 0.03 | 0.02–0.03 |
| Western Europe | 243 | 0.10 | 0.09–0.11 | 134 | 0.26 | 0.21–0.30 | 55 | 0.05 | 0.04–0.06 | 54 | 0.03 | 0.03–0.05 |
–Categories with fewer than 16 cases were suppressed.
aRates are per 100000 persons and are age adjusted to the World Health Organization Standard Million.
Abbreviations: AAAIR: average annual age-adjusted incidence rate; AYA: adolescents and young adults ages 15–39.