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. 2017 Jun 30;20(11):909–918. doi: 10.1093/ijnp/pyx055

Table 1.

Means and Highest Value (Underlined) of Maximal Blood Pressure and Heart Rate Change in Participants during Ketamine/Placebo Infusion (ΔMAX) and Mean Time to the Maximal Blood Pressure and Heart Rate Change (TΔMAX)

Ketamine
ΔMAXSys ΔMAXDia ΔMAXHr
13.38 mmHg (27 mmHg, ± 7.30) 12.65 mmHg (33 mmHg, ± 7.57) 10.69 beats/min (32 beats/min, ± 6.66)
Gender effect
18.54 mmHg (female) (± 6.79)
10.06 mmHg (male) (± 4.99)
P<.001
TΔMAXSys TΔMAXDia TΔMAXHr
28.17 min (± 9.42) 27.66 min (± 9.16) 29.39 min (± 9.25)
NET polymorphism effect
25.00 min (T) (± 8.86)
32.50 min (AA) (± 8.26)
P=.030
Gender effect
23.85 min (female) (± 8.70)
31.67 min (male) (± 6.42)
P=.017
Placebo
ΔMAXSys ΔMAXDia ΔMAXHr
6.33 min (± 5.16) 4.67 min (± 5.13) 7.10 min (± 5.00)
TΔMAXSys TΔMAXDia TΔMAXHr
15.00 min (± 12.25) 18.10 min (± 13.55) 24.31 min (± 11.00)

Significant gender and genetic differences shown in italics.