Table 1.
Ketamine | ||
---|---|---|
ΔMAXSys | ΔMAXDia | ΔMAXHr |
13.38 mmHg (27 mmHg, ± 7.30) | 12.65 mmHg (33 mmHg, ± 7.57) | 10.69 beats/min (32 beats/min, ± 6.66) |
Gender effect
18.54 mmHg (female) (± 6.79) 10.06 mmHg (male) (± 4.99) P<.001 | ||
TΔMAXSys | TΔMAXDia | TΔMAXHr |
28.17 min (± 9.42) | 27.66 min (± 9.16) | 29.39 min (± 9.25) |
NET polymorphism effect
25.00 min (T) (± 8.86) 32.50 min (AA) (± 8.26) P=.030 |
Gender effect
23.85 min (female) (± 8.70) 31.67 min (male) (± 6.42) P=.017 |
|
Placebo | ||
ΔMAXSys | ΔMAXDia | ΔMAXHr |
6.33 min (± 5.16) | 4.67 min (± 5.13) | 7.10 min (± 5.00) |
TΔMAXSys | TΔMAXDia | TΔMAXHr |
15.00 min (± 12.25) | 18.10 min (± 13.55) | 24.31 min (± 11.00) |
Significant gender and genetic differences shown in italics.