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. 2017 Oct 3;32(1):214–223. doi: 10.1038/leu.2017.275

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S1P activates Akt in HRS cells mediated by differential expression of S1P receptors. (a) Immunoblot of KMH2 cells following S1P stimulation and (b) following 1 h pre-treatment with increasing concentrations of Ozanimod or Siponimod.