Table 3.

Neurobiological Substrates of Depression Symptoms: Neural Areas Coupled with the Ventral Striatum during Loss versus Reward Events (N=68)

Symptom	R2	Predictor: Neural Area of FC with the VS	Hemis phere of VS Seed	MNI of Target Area of high connectivity with the VS	Std. β	Unst-SE	t	p	Tolera nce	VIF
Depressive Mood	0.249	Caudate, Mid Cingulate	L	−15, 0, 33	0.305	12.785	2.455	0.017	0. 798	1.253
		Precuneus, BA7	L	21, 48, 45	0.281	9.08	2.261	0.027
Anhedonia	0.155	Caudate, Mid Cingulate	L	−15, 0, 33	0.393	0.507	4.37	0.001	1	1
Suicidality	0.305	Middle & Superior Frontal Gyrus, ACC, BA8	L	30, 39, 45	0.384	1.332	3.205	0.002	0.792	1.262
		Precuneus, BA7	R	21, 48, 45	0.58	2.169	2.155	0.035
Depression Severity	0.288	Precuneus, BA7	L	21, 48, 45	0.315	12.017	2.643	0.010	0.786	1.273
		Caudate, Mid Cingulate	L	−15, 0, 33	0.312	16.203	2.670	0.010