Table 3.
Comparing steroids on incidence of infection using time dependent multivariate analysis patients treated with Cyclophosphamide
| Type of Infection | Number of Events | Cumulative Steroid (prednisone mg equivalent) Mean ± STD | P value |
|---|---|---|---|
| UTI | 0.0240** | ||
| Infection | n=7 | 13773.6 ± 7076.4 | |
| No Infection | n=35 | 11432.1 ± 5433.6 | |
| Pos. Blood Cx | 0.0394** | ||
| Infection | n=2 | 9010.8 ± 4967.4 | |
| No Infection | n=40 | 12021.9 ± 5795.6 | |
| Bacterial PNA | 0.0247** | ||
| Infection | n=2 | 17566.7 ± 11030.9 | |
| No Infection | 11546.7 ± 5417.2 | ||
| Pneumocystis carinii PNA | 0.0150** | ||
| Infection | n=1 | 23305.0 ± 0.0 | |
| No Infection | n=41 | 11554.2 ± 5484.9 | |
| Mucocutaneous Fungal Infection | 0.0544 | ||
| Infection | n=3 | 8418.3 ± 2392.4 | |
| No Infection | n=39 | 12054.8 ± 5822.8 | |
| URI | 0.0168** | ||
| Infection | n=13 | 13649.2 ± 7371.2 | |
| No Infection | n=29 | 11039.2 ± 4749.2 | |
| Mucocutaneous Bacterial Infection | 0.0216** | ||
| Infection | n=1 | 18360.0 ± 0.0 | |
| No Infection | n=41 | 11678.9 ± 5710.9 | |
| Mucocutaneous Viral Infection | 0.0113** | ||
| Infection | n=8 | 15292.3 ± 5935.1 | |
| No Infection | n=34 | 10949.1 ± 5419.5 | |
| Viral Gastroenteritis | 0.0132** | ||
| Infection | n=3 | 17584.4 ± 7008.6 | |
| No Infection | n=35 | 11373.1 ± 5457.4 |
**
Total 42 courses of cyclophosphamide in 31 patients; denominator used is 42.