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NELL family members and functional domains. This schematic shows the proposed structure of the NELL-1 and NELL-2 proteins. Both contain N-terminal TSPN domains and then a CC domain connecting to multiple VWC and EGF domains. TSPN, thrombospondin N-terminal domain; CC, Coiled Coil domain; VWC, von Willebrand factor, type C domain; EGF, EGF domain.
