Table 3.
Incidence and Remission Rates at 12 Years for Type 2 Diabetes, Hypertension, and Dyslipidemia, According to Study Group.*
| End Point | Surgery Group | Nonsurgery Group 1 | Nonsurgery Group 2 | Surgery Group vs. Nonsurgery Group 1 | Surgery Group vs. Nonsurgery Group 2 | |||
|---|---|---|---|---|---|---|---|---|
| No./Total No. | % (95% CI) | No./Total No. | % (95% CI) | No./Total No. | % (95% CI) | Adjusted Odds Ratio (95% CI)† | Adjusted Odds Ratio (95% CI)† | |
| Incidence at 12 years | ||||||||
| Type 2 diabetes | 8/303 | 3 (0 to 5) | 42/164 | 26 (16 to 35) | 47/184 | 26 (17 to 35) | 0.08 (0.03 to 0.24)‡ |
0.09 (0.03 to 0.29)‡ |
| Hypertension | 37/226 | 16 (9 to 23) | 51/123 | 41 (29 to 54) | 61/131 | 47 (34 to 59) | 0.23 (0.11 to 0.49)‡ |
0.23 (0.11 to 0.51)‡ |
| Low H DL cholesterol | 7/234 | 3 (0 to 6) | 22/130 | 17 (8 to 26) | 28/170 | 16 (8 to 24) | 0.12 (0.03 to 0.46)‡ |
0.16 (0.04 to 0.6)‡ |
| High LDL cholesterol | 53/312 | 17 (11 to 23) | 93/185 | 50 (40 to 61) | 119/213 | 56 (46 to 65) | 0.17 (0.09 to 0.31)‡ |
0.19 (0.1 to 0.36)‡ |
| High triglycerides | 3/225 | 1 (−1 to 3) | 11/137 | 8 (2 to 15) | 12/153 | 8 (2 to 14) | 0.15 (0.02 to 0.97)§ |
0.17 (0.02 to 1.15) |
| Remission at 12 years | ||||||||
| Type 2 diabetes | 43/84 | 51 (36 to 67) | 5/52 | 10 (−2 to 21) | 4/76 | 5 (−2 to 12) | 8.9 (2.0 to 40.0)‡ |
14.8 (2.9 to 75.5)‡ |
| Hypertension | 59/162 | 36 (26 to 47) | 9/93 | 10 (1 to 18) | 18/130 | 14 (5 to 22) | 5.1 (1.7 to 15.6)‡ |
2.4 (0.9 to 5.9) |
| Low HDLcholesterol | 127/154 | 82 (74 to 91) | 48/87 | 55 (40 to 70) | 49/92 | 53 (39 to 68) | 3.8 (1.6 to 9.3)‡ |
3.3 (1.3 to 8.1)¶ |
| High LDL cholesterol | 45/76 | 59 (43 to 75) | 6/32 | 19 (−1 to 38) | 3/49 | 6 (−4 to 16) | 7.1 (1.6 to 31.7)¶ |
18.6 (2.8 to 124.2)‡ |
| High triglycerides | 154/163 | 94 (89 to 100) | 44/80 | 55 (39 to 71) | 78/109 | 72 (59 to 84) | 14.7 (4.5 to 48.4)‡ |
7.0 (2.1 to 23.4)‡ |
*
The table excludes data from patients who died, patients who were lost to follow-up, and patients who later chose to undergo any type of bariatric surgical procedure.
†
The odds ratios are adjusted for age, sex, baseline body-mass index, income, education level, and marital status. Confidence intervals and significance levels were adjusted for multiple comparisons (see the Supplementary Appendix).
‡
P<0.001 for the comparison with the surgery group.
§
P<0.05 for the comparison with the surgery group.
¶
P<0.01 for the comparison with the surgery group.