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. 2017 Dec 20;12(12):e0188947. doi: 10.1371/journal.pone.0188947

Table 1. For each region, attained-age- and birth-cohort-specific annual changes in the incidence of stage 2–4 breast cancer in the 8-year period 2000–2007.

Region 1 Region 2
Attained Age*
50–54 -1% +1%
55–59 -9% +1%
60–64 -7% +4%
Age in 2000** [Born] Followed to Ages
50–54 [1946–1950] 57–61 -3% +5%
55–59 [1941–1945] 62–66 -7% +5%
60–64 [1936–1940] 69–71 -3% +4%
Reached age 50 in year** Followed to Ages
2001–2005 [1951–1955] 52–56 -5% +3%

*The first three rows show results for 3 ‘horizontal’ age-bands, each five years wide: each band contains 12 of the total of 22 birth cohorts that traverse the 3 x 5 x 8 = 120 Lexis cells.

**The remaining rows group 145 Lexis cells by birth cohorts, into 4 ‘diagonal’ bands, each one 5 birth cohorts wide (the 3 cells traversed by the birth cohorts that reached age 50 in 2006 and 2007 are omitted).

Each ‘slope’, expressed as a percentage, was derived from the coefficient of ‘year’ in the fitted Poisson/Joinpoint regression.