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. 2017 Dec 19;17:544. doi: 10.1186/s12906-017-2055-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Fold-change of kidney injury biomarkers after high- and low-dose cisplatin treatment. HMGB1 (a), NGAL (b) and KIM-1 (c) levels are shown for cells treated with 400 μM cisplatin for a short exposure time (2 to 6 h). HMGB (d), NGAL (e) and KIM-1 (f) levels were measured in cells treated with 10 μM cisplatin and a longer exposure time (6 to 48 h). The data were compared with the control condition