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. 2017 Dec 20;12(12):e0189784. doi: 10.1371/journal.pone.0189784

Fig 4. Food intake, plasma glucose and insulin in CR and AL mice.

Fig 4

(A) Mean 24h food intake ±SEM (g) and (B) Cumulative food intake over 8 weeks of body weight re-gain in mice fed ad libitum chow throughout the study (AL) and mice calorically restricted to 80% of initial body weight then released to ad libitum feeding. (C) Mean glucose and (D) insulin ±SEM in ad libitum fed (AL) or calorically restricted (CR) mice measured at 12 weeks of age while CR mice were calorically restricted to maintain 80% of initial body weight. (E) Regression of circulating insulin concentrations against fat mass in the AL and CR groups of mice at 11 weeks of age while CR were weight stable at the reduced body weight. P values: ***<0.001.