Table 2.
Biomarkers measured in this study; TD-NMR markers: plasma water T2, serum water T2
Category | Correlation with plasma water Ta2 | No correlation with plasma water Ta2 |
---|---|---|
Insulin resistance, diabetes and anthropometric markers | Fasting insulin, insulin C-peptide, proinsulin, HbA1c, glucose, HOMA-IR, QUICKI, FIRI, G/I ratio, McAuley Index | Body-mass index, waist circumference, age, resting heart rate |
Protein, viscosity liver function and amino acid markers | Total serum and plasma protein, serum and plasma globulins, % globulins, viscosity, ALT, GGT, Ser, Asn, Gln, Thr, Tyr | Serum and plasma albumin, IgG, IgM, IgA, AST, homocysteine, and 30 other amino acid and amino acid metabolites |
Lipid and lipoprotein markers | Total cholesterol, non-HDL-C, LDL-C, LDL-P, VLDL-C, IDL-C, remnant-C, apoB, phospholipids, TG, TG/HDL ratio | Lp(a), HDL-C, HDL2, HDL3, apoAI, apoE, omega-3 index, DHA, AA, EPA, LpPLA2, serum turbidity (O.D.550 nm), free fatty acids |
Inflammation, acute phase proteins, blood cell and oxidative stress markers | hs-CRP, WBC, neutrophils, lymphocytes, platelets, RDW, MCH, sedimentation rate, fibrinogen, complement C3c, C4c, plasminogen activator inhibitor-1 (PAI-1), α1-acid glycoprotein, interleukin-6 | RBC, HCT, Hb, MCHC, MCV, mean PLT volume, HNE, ORAC total antioxidant capacity, monocytes, eosinophils, basophils, haptoglobin, fibronectin, transferrin, ceruloplasmin, total iron, TIBC, % iron sat., ferritin, sICAM1, adiponectin, factor VII, uric acid, neutrophil elastase, endotoxin, staph. enterotoxin, α2-macroglobulin, α1-antitrypsin, IL-10, TNFα, IL-1β |
Electrolyte markers | Lactate, Cl−, Cl− + CO2 (bicarbonate), anion gap, anion gap corrected for albumin | Sodium, potassium, calcium |
Kidney and thyroid markers | BUN, creatinine, eGFR, thyroid stimulating hormone (TSH), free T4 |