Table 1.
Main recorded quantitative data with comparison between men and women.
| Overall (n = 60) |
Women (n = 34) |
Men (n = 26) |
p-Value | |
|---|---|---|---|---|
| Clinical and BP variables | ||||
| Age (years) | 76 ± 5.1 | 75.4 ± 4.6 | 76.5 ± 5.6 | 0.40 |
| Duration of hypertension (years) | 21.8 ± 8 | 22.6 ± 8.6 | 20.7 ± 7.3 | 0.46 |
| Number of antihypertensive medications | 2.0 ± 0.9 | 2.0 ± 0.9 | 1.9 ± 0.9 | 0.78 |
| Peripheral systolic BP (mm Hg) | 142.6 ± 17.3 | 142.7 ± 16.9 | 142.5 ± 18.2 | 0.20 |
| Peripheral diastolic BP (mm Hg) | 73.3 ± 9.6 | 72.6 ± 8.9 | 74.2 ± 10.6 | 0.15 |
| Peripheral pulse pressure (mm Hg) | 69.3 ± 12.7 | 70.1 ± 14.1 | 68.3 ± 10.6 | 0.58 |
| Central systolic BP (mm Hg)† | 134.1 ± 18.9 | 132.5 ± 19.2 | 136.3 ± 18.7 | 0.36 |
| Central pulse pressure (mm Hg)† | 59.9 ± 16.1 | 59.2 ± 17.5 | 61 ± 14.1 | 0.87 |
| Results of neuropsychological tests | ||||
| MMSE (/30) | 29.4 ± 1.1 | 29.6 ± 0.8 | 29.2 ± 1.4 | 0.25 |
| Benton score | 12.8 ± 6.8 | 14 ± 6.9 | 11.2 ± 6.5 | 0.12 |
| Gröber and Buschke free recall (/48) | 28.4 ± 7.5 | 31 ± 7 | 25 ± 6.9⁎ | < 0.01 |
| Gröber and Buschke cued recall | 17.6 ± 5.9 | 15.5 ± 5.8 | 20.3 ± 5⁎ | < 0.01 |
| Trail making test A (sec) | 47.9 ± 14.8 | 46.4 ± 12.3 | 49.8 ± 17.4 | 0.40 |
| Trail making test B (sec) | 101.1 ± 48.2 | 88.4 ± 33.1 | 116.8 ± 59⁎ | 0.04 |
| Trail making test B-A (sec) | 53.2 ± 38.6 | 42 ± 27.2 | 67 ± 46.1⁎ | 0.02 |
| Verbal fluency test score (P letter) | 12 ± 4.2 | 12.6 ± 4.7 | 11.3 ± 3.5 | 0.23 |
| Verbal fluency test score (R letter) | 11.3 ± 4.3 | 11.8 ± 4.4 | 10.8 ± 4.1 | 0.38 |
| ADCmean from overall white matter (10− 3 mm2 sec− 1) |
0.89 ± 0.05 | 0.89 ± 0.04 | 0.89 ± 0.05 | 0.45 |
| Frontal ADCmean | 0.89 ± 0.05 | 0.89 ± 0.05 | 0.90 ± 0.05 | 0.19 |
| Parietal ADCmean | 0.85 ± 0.04 | 0.86 ± 0.05 | 0.85 ± 0.04 | 0.61 |
| Temporal ADCmean | 0.85 ± 0.04 | 0.85 ± 0.04 | 0.85 ± 0.04 | 0.45 |
| Occipital ADCmean | 0.85 ± 0.04 | 0.85 ± 0.03 | 0.84 ± 0.04 | 0.17 |
| Fazekas score | 3.3 ± 1.6 | 3.4 ± 1.5 | 3.2 ± 1.7 | 0.66 |
BP, blood pressure; MMSE, mini-mental-state-examination; ADCmean, mean apparent diffusion coefficient.
⁎
p < 0.05 for comparison with women.
†
Data available for only 56 patients (24 women).