Table 2.
Volume and anatomical locations of the significant grey matter clusters obtained through SPM linear regression models aimed at correlating the CMRGlc of brain grey matter voxels with the ADCmean values obtained from the overall white matter or from the white matter of each individual lobe, and with age and gender as covariables (p-value of 0.005, corrected for cluster volume (k = 39)).
| Volume (cm3) |
Anatomical locations | |
|---|---|---|
| Overall ADCmean | 23.3 | Internal temporal areas (BA 36), posterior associative junctions (BA 18-19-21-22-39-40), posterior cingulum (BA 30-31) and insulo-opercular areas (BA 11-13-47) |
| Frontal ADCmean | 7.1 | Left prefrontal dorso-lateral area (BA46), anterior cingulum (BA 32), right associative posterior junction (BA 39) and left insulo-opercular areas (BA 13, 41, 44, 45, 47) |
| Parietal ADCmean | 23.0 | Posterior associative junctions (BA 18-19-21-22-39-40), posterior cingulum (BA 30-31) and insulo-opercular areas (BA 13-45-47) |
| Temporal ADCmean | 29.6 | Posterior associative junction (BA 18-19-21-22-39-40), posterior cingulum (BA 23-24-30-31) and insulo-opercular areas (BA 13-44-45-47) |
| Occipital ADCmean | 29.4 | Internal temporal areas (BA 36), posterior associative junctions (BA 18-19-39-40), posterior cingulum (BA 30-31), and insulo-opercular areas (BA 13-44-45-47) |
ADCmean, mean apparent diffusion coefficient; BA, Brodmann areas.