Table 3.

Pearson coefficients between the ADC_mean of the overall white matter or the CMRGlc of areas correlated with global ADC_mean, and clinical and BP variables and neuropsychological test scores.

	Global ADCmean	p-Value	CMRGlc	p-Value
Clinical and BP variables
Age (years)	0.522⁎	< 0.01	− 0.315⁎	0.01
Duration of hypertension (years)	0.243	0.06	− 0.109	0.41
Number of antihypertensive medications	0.041	0.76	− 0.144	0.27
Peripheral systolic BP (mm Hg)	0.272⁎	0.04	− 0.210	0.11
Peripheral diastolic BP (mm Hg)	0.234	0.07	− 0.142	0.28
Peripheral pulse pressure (mm Hg)	0.194	0.14	− 0.178	0.17
Central BP (mm Hg)†	0.388⁎	< 0.01	− 0.362⁎	0.01
Central pulse pressure (mm Hg)†	0.302⁎	0.02	− 0.244	0.07
Neuropsychological test scores
MMSE (/30)	− 0.173	0.19	0.262⁎	0.04
Benton score	− 0.045	0.73	0.056	0.67
Gröber and Buschke free recall (/48)	− 0.432⁎	< 0.01	0.498⁎	< 0.01
Gröber and Buschke cued recall	0.429⁎	< 0.01	− 0.406⁎	< 0.01
Trail making test A (sec)	0.435⁎	< 0.01	− 0.333⁎	< 0.01
Trail making test B (sec)	0.384⁎	< 0.01	− 0.518⁎	< 0.01
Trail making test (B-A) (sec)	0.300⁎	0.02	− 0.534⁎	< 0.01
Verbal fluency test score (P letter)	− 0.250	0.05	0.217	0.10
Verbal Fluency Test score (R letter)	− 0.235	0.07	0.202	0.12

BP, blood pressure; MMSE, mini-mental-state-examination; ADC_mean, mean apparent diffusion coefficient; CMRGlc, cerebral metabolic rate of glucose.

^⁎For significant relationships with p < 0.05.

^†Data available for only 56 subjects (24 women).