Table 3.

Participant characteristics with positive EMA results

Case/Control Status	Gender	Age	Region1	Rome Status	IBS subtype	Bowel habit <30d	Age IBS diagnosis	IBS family history	Celiac family history	HLA- DQ2.5 result	HLA- DQ8 result
Case	Male	51	3	Neg	N.A.	Normal	492	No	No	Yes	No
Case	Male	66	2	Neg	N.A.	Other	41	Yes	No	Yes	No
Case3	Female	24	1	Pos	IBS-M	Mixed	24	No	No	Yes	No
Case3	Female	43	2	Pos	IBS-C	Mixed	43	Yes	No	Yes	No
Case3	Female	51	1	Pos	IBS-M	Constip	45	No	No	Yes	No
Case	Female	69	2	Pos	Cannot determine	Constip	31	Yes	No	No	Yes
Control	Male	45	2	Neg	-	Normal	-	No	No	Yes	No
Control	Female	33	1	Neg	-	Normal	-	No	Yes	Yes	No
Control	Female	64	2	Neg	-	Normal	-	Yes	No	Yes	No

¹Region: 1=local, 2=regional, 3=national

²Age of IBS symptom onset

³Small bowel biopsy-confirmed celiac

IBS, Irritable bowel syndrome; Neg, Negative; Pos, Positive, N.A., Not applicable; IBS-M, Irritable bowel syndrome-mixed, IBS-C, Irritable bowel syndrome-constipation, Constip, Constipation