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. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: Pharm Res. 2017 Aug 14;34(12):2663–2674. doi: 10.1007/s11095-017-2237-9

(A) Circular dichroism spectra of commercial BSA in water, BSA mixed with PVP30 in spray solution and BSA reconstituted right after spray layering. MRE stands for Mean Residue Ellipticity.

(B) Secondary structure components of BSA right after spray layering and after 38 days storage at 4 °C, 25 °C/60% RH and 40 °C/75% RH.

(A) Circular dichroism spectra of commercial BSA in water, BSA mixed with PVP30 in spray solution and BSA reconstituted right after spray layering. MRE stands for Mean Residue Ellipticity.

(B) Secondary structure components of BSA right after spray layering and after 38 days storage at 4 °C, 25 °C/60% RH and 40 °C/75% RH.