Table 2.
Symptom Frequency
| Overall | Frequency by Age Group* - n (frequency %) | |||
|---|---|---|---|---|
| Frequency (%) | <50 years (n = 200) | =>50 years (n =354) | p+ | |
| Overall low energy or fatigue | 523 (8.6) | 147 (73.5) | 239 (67.5) | 0.1688 |
| Muscle aches/pain | 438 (7.2) | 112 (56.0) | 200 (56.5) | 0.9807 |
| Depression (eg. Feeling worthless, hopeless) | 391 (6.4) | 111 (55.5) | 174 (49.2) | 0.1779 |
| Anxiety or fear (e.g. feeling nervous) | 335 (5.5) | 91 (45.5) | 152 (42.9) | 0.6209 |
| Difficulty staying asleep | 335 (5.5) | 91 (45.5) | 157 (44.4) | 0.8631 |
| Difficulty falling asleep | 323 (5.3) | 102 (51.0) | 122 (34.5) | 0.0001999+ |
| Neuropathy (Numbness or tingling in hands/feet) | 296 (4.8) | 60 (30.0) | 159 (44.9) | 0.0007844+ |
| Decreased sex drive | 276 (4.5) | 59 (29.5) | 148 (41.8) | 0.005358 |
| Difficulty remembering things | 270 (4.4) | 65 (32.5) | 129 (36.4) | 0.4003 |
| Difficulty concentrating/Easily distracted | 237 (3.9) | 69 (34.5) | 113 (31.9) | 0.5985 |
| Problems achieving or maintaining an erection (Male only) | 237 (3.9) | 38 (19.0) | 134 (37.9) | 6.459e-06+ |
| Shortness of breath with activity | 229 (3.8) | 61 (30.5) | 104 (29.4) | 0.8567 |
| Diarrhea | 229 (3.8) | 71 (35.5) | 91 (25.7) | 0.01945 |
| Thirst/Dry mouth | 200 (3.3) | 58 (29.0) | 91 (25.7) | 0.4593 |
| Constipation/Gas/Bloating | 189 (3.1) | 52 (26.0) | 85 (24.0) | 0.6755 |
| Lightheadedness/Dizziness | 175 (2.9) | 51 (25.5) | 74 (20.9) | 0.2555 |
| Clumsy walking/Balance difficulty/Dropping things frequently | 167 (2.7) | 36 (18.0) | 88 (24.9) | 0.07941 |
| Dry eyes | 158 (2.6) | 41 (20.5) | 81 (22.9) | 0.5872 |
| Unplanned weight loss/gain | 157 (2.6) | 54 (27.0) | 59 (16.7) | 0.005283 |
| Heartburn/Reflux | 154 (2.5) | 42 (21.0) | 72 (20.3) | 0.9399 |
| Ringing in ears/Noise intolerance | 150 (2.5) | 34 (17.0) | 80 (22.6) | 0.1453 |
| Cough | 129 (2.1) | 33 (16.5) | 45 (12.7) | 0.2696 |
| Changes in appetite | 118 (1.9) | 35 (17.5) | 51 (14.4) | 0.399 |
| Nausea/Vomiting | 111 (1.8) | 44 (22.0) | 38 (10.7) | 0.0005367+ |
| Difficulty with urination | 105 (1.7) | 16 (8.0) | 63 (17.8) | 0.00236 |
| Fevers/Night sweats/chills | 94 (1.5) | 32 (16.0) | 36 (10.2) | 0.06095 |
| Speech difficulties (eg. slowed speech, reversing numbers, words, letters) | 62 (1.0) | 15 (7.5) | 32 (5.9) | 0.6413 |
| Pain or discomfort during sex | 23 (0.4) | 9 (4.5) | 8 (2.3) | 0.2256 |
| Total | 6111 | |||
*
Not all participants reported their age and so total frequency by age group does not equal the overall frequency
+
after correcting for multiple comparisons a significant p-value at 95% confidence is 0.00089