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. 2017 Dec 20;5:52. doi: 10.1186/s40635-017-0165-y

Table 3.

Blood gas parameters during hemorrhage and fluid resuscitation

Group T bsl T 0 T 1 T 2 T 3 T 4
pH HES 7.613 ± 0.038# 7.603 ± 0.061# 7.568 ± 0.068# 7.54 ± 0.052 7.513 ± 0.043*† 7.519 ± 0.042*†
RF 7.541 ± 0.049 7.498 ± 0.063 7.448 ± 0.055*† 7.393 ± 0.161* 7.464 ± 0.055* 7.48 ± 0.061*
PaCO2 (mmHg) HES 28.1 ± 3.2 24.3 ± 3.8# 26.1 ± 4.6# 28.4 ± 4.4#† 29.9 ± 3.1#† 30.8 ± 4.5†
RF 33.8 ± 5.3 33.9 ± 7.4 39.1 ± 6.8† 38.6 ± 6.8† 39.4 ± 6.6† 38.3 ± 6.0†
PaO2 (mmHg) HES 87.5 ± 12.2† 102.8 ± 11.0* 100.4 ± 9.6* 95.8 ± 8.7 90.3 ± 13.0† 84.5 ± 14.6†
RF 99.0 ± 24.7 102.0 ± 25.7 96.7 ± 27.8† 99.2 ± 29.3 94.9 ± 27.5 99.6 ± 30.9
HCO− 3 (mmol/l) HES 27.6 ± 2.3† 24.4 ± 1.8* 23.0 ± 1.5#* 23.1 ± 2.0* 23.5 ± 1.2#* 24.4 ± 1.7#*
RF 28.1 ± 1.4 25.5 ± 4.0 26.3 ± 3.3 26.6 ± 3.6 27.5 ± 2.7† 27.7 ± 2.5†
SaO2 (%) HES 97.8 ± 0.4 98.4 ± 0.3 98.2 ± 0.3 98 ± 0.4 97.7 ± 0.5 97.7 ± 0.4
RF 97.8 ± 1.2 97.8 ± 1.1 96.5 ± 2.7† 96.9 ± 2.4 96.8 ± 2.2† 96.8 ± 2.6
Lactate (mmol/L) HES 3.8 ± 2.0† 6.9 ± 3.7* 8.1 ± 3.0#*† 7.6 ± 2.2#* 7.1 ± 2.0#* 5.5 ± 1.9#*†
RF 2.1 ± 0.8† 4.3 ± 2.0* 4.7 ± 2.0* 4.2 ± 1.8* 3.8 ± 1.7* 3.3 ± 1.4*
Hct (%) HES 30.0 ± 4.8 26.7 ± 5.3 23.8 ± 5.2*† 22.5 ± 4.5*† 20.6 ± 3.5*† 19.3 ± 3.9*†
RF 34.5 ± 4.6† 30.5 ± 5.6* 27.1 ± 4.5*† 25.1 ± 3.9*† 23 ± 2.6*† 22.4 ± 3.1*†
Hb (g/dL) HES 9.8 ± 1.2 8.9 ± 1.4 8.1 ± 1.5*† 7.7 ± 1.3*† 7.1 ± 0.9*† 6.7 ± 1.0*†
RF 10.9 ± 1.2 9.9 ± 1.6 9 ± 1.3*† 8.4 ± 1.1*† 7.7 ± 0.9*† 7.7 ± 1.0*†
Ca++ (mmol/L) HES 0,87 ± 0,18 0,84 ± 0,23 0,84 ± 0,17 0,82 ± 0,24 0,84 ± 0,23 0,87 ± 0,29
RF 0,93 ± 0,3 0,87 ± 0,2 0,94 ± 0,23 0,86 ± 0,25 0,91 ± 0,31 0,89 ± 0,27
K+ (mmol/L) HES 2,48 ± 0,32 2,96 ± 0,49 3,04 ± 0,38* 2,98 ± 0,29* 2,9 ± 0,44 2,8 ± 0,48
RF 2,84 ± 0,44 3,11 ± 0,33 3,33 ± 0,34*† 3,24 ± 0,27 3,22 ± 0,32 3,2 ± 0,27
Na+ (mmol/L) HES 139,9 ± 1,2 139,5 ± 1,2 140,7 ± 0,7† 141,1 ± 1*† 141,1 ± 0,9† 141,2 ± 0,8†
RF 138,9 ± 3,2 138,8 ± 3,2 139,7 ± 3,1† 139,8 ± 2,8† 139 ± 4,3 140,3 ± 2,9*†
Cl− (mmol/L) HES 98 ± 1,9 98,7 ± 2,2 99,9 ± 1,7*† 100,4 ± 1,3*† 101,1 ± 1,8*† 101,7 ± 1,5*†
RF 97,1 ± 2,4 98,1 ± 2,7 99,6 ± 2,7*† 100,4 ± 2,3*† 100,4 ± 2,4*† 102 ± 2,9*†
Glucose (mmol/L) HES 8,1 ± 2,2 9,3 ± 3,5 6,8 ± 2,3† 6 ± 1,8† 6,4 ± 1† 6,8 ± 0,8†
RF 9 ± 2,9 10,9 ± 3,3 7,6 ± 3,3† 6,4 ± 2,9*† 6,2 ± 1,9*† 6,1 ± 1,4*
cv pH HES 7.578 ± 0.039# 7.537 ± 0.07# 7.516 ± 0.069# 7.49 ± 0.047#*† 7.476 ± 0.035*† 7.495 ± 0.034*
RF 7.503 ± 0.049† 7.416 ± 0.049* 7.39 ± 0.047*† 7.41 ± 0.05* 7.427 ± 0.055* 7.442 ± 0.051*
PcvCO2 (mmHg) HES 31.4 ± 2.7# 30.3 ± 4.7# 30.8 ± 5.3# 31.7 ± 3.6# 33.2 ± 3.7# 33 ± 3.7#
RF 39.4 ± 7.6 43.2 ± 7.6 47.6 ± 6.9*† 46.1 ± 7.1 44.3 ± 7.5 42.1 ± 6.6
PcvO2 (mmHg) HES 46.7 ± 8.1† 36.0 ± 9.9* 40.7 ± 7.8*† 44.5 ± 7.8† 46.8 ± 5.2† 45.4 ± 8.7†
RF 48.3 ± 7.2† 34.9 ± 4.0* 39.3 ± 4.1*† 44.8 ± 3.3† 46.2 ± 5.2† 48.6 ± 6.7†
ScvO2 (%) HES 83.9 ± 7.3† 69.1 ± 14.2* 76.0 ± 9.9* 79.7 ± 5.9*† 82.6 ± 4.2† 82.8 ± 4.8†
RF 83.5 ± 8.1† 59.9 ± 6.6* 65.7 ± 7.9* 72.7 ± 7.4*† 76.2 ± 6.4*† 79.0 ± 8.1*†
Oxygen delivery index (mL/min/m2) HES 431.7 ± 83.9† 203.5 ± 48.3* 271.8 ± 55.7*† 295.1 ± 59.8*† 322.4 ± 60.7*† 348.1 ± 57.7*†
RF 460.3 ± 43.0 251.9 ± 83.5* 269.2 ± 70.6* 282.0 ± 54.6* 296.4 ± 44.8*† 354.6 ± 61.6*†
Oxygen consumption
(index mL/min/m2)		 HES 58.6 ± 26.8 58.7 ± 27.6 62.3 ± 34.7 55.0 ± 21.8 49.7 ± 16.2 52.9 ± 20.5
RF 65.2 ± 32.9† 97.5 ± 36.9* 85.3 ± 22.5* 69.4 ± 16.5† 63.4 ± 23.5† 65.5 ± 31.0†
Oxygen extraction (%) HES 14.2 ± 7.2† 29.8 ± 14.2* 22.6 ± 9.9* 18.6 ± 6.0† 15.5 ± 4.5† 15.2 ± 5.1†
RF 14.5 ± 8.2† 38.8 ± 6.8* 32.0 ± 7.1* 25.0 ± 6.2*† 21.3 ± 6.5*† 18.4 ± 8.3*†
Venous to arterial carbon dioxide gap (mmHg) HES 3.3 ± 1.4† 6.0 ± 2.8#* 4.7 ± 2.0# 3.3 ± 1.9#† 3.3 ± 1.2† 2.2 ± 1.2†
RF 5.6 ± 3.4† 9.3 ± 1.6* 8.5 ± 1.7*† 7.5 ± 2.6 4.9 ± 2.0† 3.8 ± 2.2*†

Data are presented as mean ± standard deviation. HES = colloid group, RF = crystalloid group

*p < 0.05 significantly different from T bsl

† p < 0.05 significantly different from T 0

# p < 0.05 significantly different between groups