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. 2017 Dec 20;7:17893. doi: 10.1038/s41598-017-18091-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Histograms of NGS enriched regions with an overlap greater than 0.5 Mb with a NotI fragment in the specified range. Results are shown for fractions 5, 7 and 9. The total number of NGS enriched regions was 178, 228, and 306, respectively. Points with error bars show the average number of counts and the standard deviations from a random permutation of NGS enriched regions for the same number of NGS enriched regions and with the same size distribution as in the experiment. The total number of overlaps in the experiments and the simulations are stated in the figures.