Table 1.
Genomic features of EC1002 and EC2474.
| Chromosome/plasmid | Plasmid replicon type | Size (bp) | GC content (%) | Accession numbers | CDS | Resistance genes a |
|---|---|---|---|---|---|---|
| EC1002 | — | 5,177,501 | 50.1 | CP021202 | 4,808 | bla CTX-M-15, oqxB, tetB, |
| pEC1002-1 | IncFII | 183,509 | 50 | CP021203 | 234 | bla CTX-M-15, sul, mph, aac(3)-Ib, erm, aadA4, dfrA, arr |
| pEC1002-MCR | IncI2 | 63,392 | 43 | CP021205 | 97 | mcr-1 |
| pEC1002-NDM | IncA/C2 | 111,688 | 52.3 | CP021206 | 154 | bla NDM-1, bla CTX-M-14, bla TEM, sul1, mph, aac(6′)-Ib, rmtc, arr |
| pEC1002-4 | IncFIB | 92,439 | 50 | CP021204 | 136 | bla TEM |
| EC2474 | — | 5,013,813 | 50.6 | CP021207 | 4,938 | bla CTX-M-55 |
| pEC2474-MCR | IncHI2 | 223,982 | 45.8 | CP021209 | 284 | mcr-1, bla CTX-M-14, floR, aph4, sul2, aac(3)-IVa, fosA14 |
| pEC2474-NDM | IncFII | 75,553 | 50.8 | CP021210 | 110 | bla NDM-1, aph |
| pEC2474-3 | IncI1 | 86,717 | 49.5 | CP021208 | 124 | bla CTX-M-55 |
aaac(3)-IB: aminoglycoside acetyltransferase-IB; aad: aminoglycoside adenylyltransferase; adrA: dihydrofolate reductase; aph: aminoglycoside-3′-O-phosphotransferase; arr: rifampin ADP-ribosylating transferase; erm: erythromycin resistance methylase; oqxB: olaquindox resistance; tetB: tetracycline resistance; fosA: glutathione transferase; mph: macrolide phosphotransferases; rmtC: ribosomal RNA methyltransferase; sul: sulphonamide resistance.