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. 2017 Dec 20;7:17888. doi: 10.1038/s41598-017-17982-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relationship between MMP-9, CK, age and 6MWD at baseline in the phase 3 study (NCT01254019 - DMD114044). (A,C,E) Scatter plots showing the relationship between MMP-9 serum levels with age, 6MWD and the combination of age and 6MWD data. (B,D,F) Scatter plots showing the relationship between CK activity levels with age, 6MWD and the combination of age and 6MWD data. In panels E and F, color represents age windows as shown by the legend at the bottom-right and 6MWD are plotted for each age bin.