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. 2017 Aug 16;5(1):15–30. doi: 10.1016/j.jcmgh.2017.08.001

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

(A) Differential expression of inflammation/immune-related genes in the mouse intestine 7 days after irradiation. Hierarchical clustering analyses were performed and the results were visualized in the heat map. (B) Individual fold change determined for a panel of genes demonstrating a reduced inflammatory response in the irradiated HIF-1α^FL/FL group compared with the HIF-1α^FL/FL VEcad-Cre^+/- group. (C) Volcano plot analyses between the irradiated HIF-1α^FL/FL group and the irradiated HIF-1α^FL/FLVEcad-Cre^+/- group (fixed fold change 1.5 and P = .05). (D) Hierarchical clustering analyses were performed and a heat map was generated with 6 molecular entities. SEL-P, Selectin-P; TNF, tumor necrosis factor; VEGF, vascular endothelial growth factor.