Figure 6.
Micro-structure and micro-mechanics of the aorta. Structural images on the left show the presence of local fibrous nodules (arrows) and lipid (asterisk). Stiffness elastograms (right) on a log10 scale overlaid on the structural images show the localized stiffening in fibrous regions and softening in lipid-rich regions. Magnified insets at far right illustrate the characteristic signature of fibrous tissue and lipid in OCM (taken from aorta images not shown here). All images are from knockout mice. The scale bars represent 200 μm, and 100 μm in the insets. To see this figure in color, go online.