Table 2.
Operative results of PHPT patients by tumor clonal status (N = 82)
| Feature | Monoclonal | Polyclonal | P value |
|---|---|---|---|
| Clonal Status | 43 (52%) | 39 (48%) | |
| Operative approach | 0.556 | ||
| UNE | 16 (37%) | 17 (43%) | |
| BNE | 27 (63%) | 22 (57%) | |
| % ioPTH drop | 67 | 69 | 0.787 |
| ioPTH slope (B2 – PTH10) | −14 | −16 | 0.691 |
| Final ioPTH level (mean &range, pg/ml) | 40 | 43 | 0.886 |
| Glands abnormal | |||
| Single | 40 (93%) | 30 (77%) | |
| Multiple | 3 (7%) | 9 (23%) | 0.039 |
| Gland weight** (mean, mg) | 830 | 873 | 0.738 |
| Persistent PHPT (%) | 1 (2%) | 2 (5%) | 0.355 |
| Post-op serum Ca+2 (mean, mg/dl;N=49) | 9.4 | 9.5 | 0.659 |
| Post-op Intact PTH (mean, pg/ml;N=45) | 57 | 70 | 0.927 |
UNE, unilateral neck exploration; BNE, bilateral neck exploration.
*
B2, baseline 2 defined as PTH level drawn prior to removal of the index parathyroid tumor; PTH10, intra-operative PTH drawn 10 minutes after removal of the index gland; slope = B2-PTH10/10
**
weight of gland (index tumor) used to determine clonal status