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. 2017 Oct 26;15(1):99–108. doi: 10.3892/ol.2017.7281

Table IV.

Association between nuclear claudin expression and clinicopathological characteristics of colorectal adenocarcinoma in 100 tissue samples from patients.

Claudin-3 expression Claudin-7 expression


Characteristics (−) (+) P-value (−) (+) P-value
Age, years 0.563 1.000
  <60 16   6 22 0
  ≥60 62 16 76 2
Sex 0.088 0.511
  Male 50 9 57 2
  Female 28 13 41 0
Histological type 0.001 0.345
  Well- to moderately-differentiated 69 12 80 1
  Mucinous   9 10 18 1
Lymphatic invasion 0.867 0.526
  Negative 25 6 30 1
  Positive 53 16 68 1
Venous invasion 0.370 1.000
  Negative 14 6 20 0
  Positive 64 16 78 2
Lymph node metastasis 0.794 0.777
  N0 52 13 63 2
  N1 21 7 28 0
  N2   4 2   6 0
  N3   1 0   1 0
Depth of tumor invasion 0.181 0.319
  Tis   1 0   1 0
  T1   8 2   9 1
  T2   4 2   6 0
  T3 45 7 52 0
  T4 20 11 30 1
Stage 0.350 0.662
  0   1 0   1 0
  I 11 4 14 1
  II 40 9 48 1
  III 26 8 34 0
  IV   0 1   1 0