Table I.
Associations between general clinical variables and CNP in hepatocellular carcinoma patients undergoing radiofrequency ablation.
| Variables | CNP0 (n=118) | CNP1 (n=81) | CNP2 (n=88) | P-value |
|---|---|---|---|---|
| Sex | 0.258 | |||
| Male | 89 | 65 | 61 | |
| Female | 29 | 16 | 27 | |
| Age, years | 0.352 | |||
| ≤55 | 51 | 43 | 39 | |
| >55 | 67 | 38 | 49 | |
| HBsAg | 0.606 | |||
| Positive | 72 | 53 | 51 | |
| Negative | 46 | 28 | 37 | |
| Liver cirrhosis | 0.015 | |||
| Presence | 79 | 63 | 74 | |
| Absence | 39 | 18 | 14 | |
| Number of tumors | 0.798 | |||
| 1 | 87 | 58 | 67 | |
| ≥2 | 31 | 23 | 21 | |
| Tumor diameter, cm | 0.824 | |||
| ≤3 | 76 | 55 | 56 | |
| 3–5 | 42 | 26 | 32 | |
| Tumor location near intrahepatic vessels | 0.761 | |||
| Yes | 41 | 30 | 35 | |
| No | 77 | 51 | 53 | |
| Child-Pugh class | 0.024 | |||
| A grade | 92 | 61 | 54 | |
| B grade | 26 | 20 | 34 | |
| AFP, ng/ml | 0.690 | |||
| <400 | 43 | 34 | 36 | |
| ≥400 | 75 | 47 | 52 | |
| Prothrombin time prolongation, sec | 0.163 | |||
| ≤3 | 71 | 48 | 42 | |
| >3 | 47 | 33 | 46 |
CNP, combination of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio; HBsAg, hepatitis B surface antigen; AFP, α-fetoprotein.