Lipid A modifications in lptA41 suppressor strains. MALDI-TOF profiles of lipid A isolated from wild-type strain AM604 (A and B) treated (B) or not treated (A) with EDTA, PS001 (lptA+) (C), PS003 (lptA41) (D), and suppressor strains PS102 (mlaA102) (E) and PS103 (lptA42/opgH103) (F). The percent intensity relative to the most abundant species for each peak is reported. The inset plots show 10-fold-magnified views of the region around m/z 1,800 to 2,050. Relevant lipid A species are indicated. For details, see Materials and Methods.