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. 2017 Dec 20;12:35. doi: 10.1186/s13020-017-0159-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Pathway analysis and integrative analysis. a Pathway enrichment analysis of differential metabolites form LPS/GALN and LPS/GALN + HD using an online tool, Metaboanalyst 3.0 (http://www.metaboanalyst.ca/). Significantly enriched pathways are selected to plot. b Integrative analysis of metabolites in significantly enriched pathways. Up-regulation and down-regulation of metabolites are indicated as red and green, respectively. The number reveals the ratio of differential metabolites