Table 1.

Physichochemical properties of sesamol-loaded NLCs

Formulation code	Particle size (nm)	PDI	ZP (mV)	EE (%)	DL (%)	DR after 48 h (%)
S-NLC1 S-NLC2 S-NLC3 S-NLC4 S-NLC5 S-NLC6 S-NLC7 S-NLC8 Blank NLCs	137.4 ± 9.2 123.6 ± 7.4 104.3 ± 8.7 66.3 ± 1.6 73.8 ± 4.3 81.6 ± 3.7 92.3 ± 6.2 124.7 ± 9.4 52.4 ± 6.7	0.37 ± 0.04 0.32 ± 0.01 0.28 ± 0.03 0.12 ± 0.07 0.18 ± 0.07 0.21 ± 0.05 0.23 ± 0.04 0.29 ± 0.09 0.13 ± 0.06	−21.8 ± 0.51 −26.2 ± 0.37 −23.3 ± 0.63 −25.8 ± 0.58 −21.4 ± 0.47 −19.5 ± 0.53 −27.9 ± 0.56 −25.4 ± 0.45 −18.7 ± 0.72	41.4 ± 2.6 47.7 ± 3.2 66.3 ± 8.5 94.3 ± 3.7 92.7 ± 4.3 89.2 ± 6.4 94.2 ± 1.8 91.4 ± 2.5 _	1.45 ± 0.14 1.63 ± 0.08 1.78 ± 0.12 3.11 ± 0.06 6.13 ± 0.17 11.32 ± 3.4 28.51 ± 1.2 49.92 ± 3.7 _	52.7 ± 4.8 57.3 ± 5.3 68.5 ± 4.7 82.3 ± 5.7 77.8 ± 6.2 74.6 ± 3.9 69.8 ± 5.4 60.3 ± 1.8 _

Data are represented as mean ± SEM (n = 6)

(PDI polydispersity index, ZP zeta potential, EE entrapment efficiency, DL drug loading, DR drug release, S-NLCs sesamol-loaded nanostructured lipid carriers)