Table 2.
Identification or erythrocyte proteins that bound to PF3D7_0402000 by co-affinity purification plus mass spectrometry
| Protein Name | Gene Name | Spectral Counts* | Control Spectral Counts* | Fold Enrichment** | Saint Score | BFDR *** |
|---|---|---|---|---|---|---|
| W4J5J2 | PF3D7_0402000 | 248|182 | 0|1 | 430 | 1 | 0 |
| P11171 | EPB41 | 145|160 | 27|22 | 6.22 | 1 | 0 |
| P16157 | ANK1 | 36|15 | 0|0 | 255 | 1 | 0 |
| P04406 | GAPDH | 28|22 | 0|2 | 25 | 1 | 0 |
| P68871 | HBB | 16|8 | 0|0 | 120 | 1 | 0 |
| P04040 | CAT | 19|4 | 0|1 | 23 | 1 | 0 |
| P16452 | EPB42 | 10|12 | 0|0 | 110 | 1 | 0 |
| Q08495 | DMTN | 10|9 | 1|1 | 9.5 | 1 | 0 |
| P69905 | HBA1 | 12|4 | 1|1 | 8 | 0.99 | 0 |
| Q00577 | PURA | 7|7 | 0|0 | 70 | 1 | 0 |
| Q9UKV8 | AGO2 | 5|5 | 0|0 | 50 | 1 | 0 |
| P11166 | SLC2A1 | 3|5 | 0|0 | 40 | 1 | 0 |
| P02730 | SLC4A1 | 3|4 | 0|0 | 35 | 1 | 0 |
| P60709 | ACTB | 4|2 | 1|1 | 3 | 0.93 | 0 |
| P11142 | HSPA8 | 3|3 | 0|0 | 30 | 1 | 0 |
| P16403 | HIST1H1C | 2|3 | 1|1 | 2.5 | 0.92 | 0.01 |
*
Spectral counts from two replicates are shown (Replicate 1|Replicate 2)
**
Fold enrichment was calculated by dividing the average of the spectral counts from the MBP-PF3D7_0402000 co-purification by that of the MBP-His co-purification. If the prey protein was not detected in the MBP-His co-purification, the average spectral counts from the MBP-PF3D7_0402000 co-purification was divided by 0.1.
***
BFDR, Bayesian False Discovery Rate