Table 3.
ROI | ROI Volumea | ROI Volume Ratioa | Rho (P value)b |
---|---|---|---|
|
|||
Thalamus | 15.25 ± 1.96 | 0.010 ± 0.001 | −0.438 (0.029) |
Striatum | 18.05 ± 2.21 | 0.012 ± 0.002 | −0.605 (0.001)* |
Hippocampus | 8.48 ± 0.80 | 0.006 ± 0.001 | −0.242 (0.243) |
Cerebellar CTX | 104.83 ± 16.06 | 0.070 ± 0.009 | −0.304 (0.140) |
Temporal CTX | 92.37 ± 13.20 | 0.061 ± 0.007 | −0.737 (< 0.001)* |
Occipital CTX | 42.98 ± 5.17 | 0.029 ± 0.003 | −0.562 (0.003)* |
Cingulate CTX | 19.44 ± 3.31 | 0.013 ± 0.001 | −0.710 (< 0.001)* |
Frontal CTX | 165.69 ± 22.78 | 0.110 ± 0.009 | −0.758 (< 0.001)* |
Parietal CTX | 103.95 ± 13.60 | 0.069 ± 0.005 | −0.627 (0.001)* |
Total ICV | 1509.79 ±169.20 | N/A | N/A |
Presented as Mean ± Standard Deviation. ROI volume is in units of cm3. Volume relative to total intracranial volume (ICV) is defined as volume ratio and is unitless.
Spearman’s rank correlation analysis was applied to each test of correlation between age and ROI volume ratio. Cortex, CTX; Region of Interest, ROI.
P < 0.0056, which marks significance after applying Bonferroni correction for the nine regions tested.