Table 2.

Clinical samples used in the study.

		DNA methylation analysis
				In silico analysis
		Pyrosequencing	ML	Methylcapture sequencing data	Methylation array data from TCGA data	Methylation array data from GEO (GSE48684)	Protein expression analysis
Colorectal tissue	Normal		11			17	11
	NAT	15		6	39
	Adenoma	15	11	15		42	11
	CRC	15	10	9	39	64	10
Plasma	Normal		47
	Adenoma		37
	CRC		37
	∑	45	153	30	78	123	32

ML: MethyLight reaction; NAT: Normal adjacent tissue; CRC: Colorectal cancer; TCGA: The Cancer Genome Atlas; Gene Expression Omnibus