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. 2017 Nov 24;12(9):793–803. doi: 10.1080/15592294.2017.1342912

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Hypomethylated blocks in placenta and cancer. (A) The light green zone shows an illustrative placenta hypomethylated block representing a difference in average methylation between first trimester (solid line) and third trimester (dashed line) chorionic villi samples. Gene loci are marked in yellow. (B) The light green zone shows an illustrative cancer hypomethylated block representing a difference in average methylation between colon adenocarcinoma tumor (solid line) and corresponding normal tissue (dashed line) samples. Gene loci are marked in yellow. (C) Distributions of the lengths of placenta hypomethylated blocks in pink and cancer hypomethylated blocks (colon adenocarcinoma) in purple. (D) Distributions of the number of genes per placenta hypomethylated blocks in pink, and cancer hypomethylated blocks in purple (colon adenocarcinoma). Abbreviations as in Table 1.