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. 2016 Dec 5;16(4):585–596. doi: 10.1177/1534735416681638

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — β-Lapachone induces G0/G1 phase cell cycle arrest through inhibition of cyclin D1 and CDK4 expression. (A) Cell cycle analysis of CT26 cells after treatment with β-lapachone for 24 hours. Data are representative of 3 independent experiments. (B) Percentages of cells with the DNA content consistent with each phase of the cell cycle were plotted. (C) mRNA expression of cyclin D1 and CDK4. CT26 cells were treated with various concentrations of β-lapachone for 24 hours. Results are expressed as the mean ± SD of 3 independent experiments. *P < .05.