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. Author manuscript; available in PMC: 2017 Dec 21.
Published in final edited form as: Food Chem Toxicol. 2007 Sep 22;46(2):628–636. doi: 10.1016/j.fct.2007.09.093

Fig. 2.

Fig. 2

(A) Comparison of the percentage of mutational types for all (large and small) colonies produced in mouse lymphoma cells untreated or treated with acrylamide (16 mM) or glycidamide (4 mM). The data are the weighted sum of mutant frequencies from large and small colonies (the proportion of small colony mutants was 64% for acrylamide and 57% for glycidamide). The data for the untreated control are from the literature (36). For the mutational spectra, the treatment groups were significantly different from the untreated control (P < 0.0001), and there was also a significant difference between the two treatment groups (P < 0.05). (B) The loci that were analyzed for LOH (Tk1, D11Mit59, D11Mit22, and D11Mit74) are marked. The ruler in centimorgans indicates the distance from the top of the chromosome.