Table 2.
LOH at different loci along chromosome 11 in 48 large- and 48 small-colony Tk mutants from cells treated with acrylamide or glycidamide
| Locus | Position (cM)b | Acrylamide | Glycidamide | Controla | |||
|---|---|---|---|---|---|---|---|
|
|
|
|
|||||
| No. in large colonies (%) | No. in small colonies (%) | No. in large colonies (%) | No. in small colonies (%) | No. in large colonies (%) | No. in small colonies (%) | ||
| D11Mit74 | 0 | 9 (19) | 6 (13) | 5 (10) | 4 (8) | 5 (14) | 9 (27) |
| D11Mit22 | 25 | 15 (31) | 9 (19) | 7 (15) | 4 (8) | 7 (19) | 13 (39) |
| D11Mit59 | 56 | 27 (56) | 11 (23) | 29 (60) | 6 (13) | 11 (31) | 18 (55) |
| Tk | 78 | 48 (100) | 48 (100) | 45 (94) | 48 (100) | 15 (42) | 32 (97) |
| Non-LOHc | 0 (0) | 0 (0) | 3 (6) | 0 (0) | 21 (58) | 1 (3) | |
a
The negative control data are from the literature (Wang et al., 2007).
b
Locus position in centimorgan (cM) is the distance to the top of chromosome 11.
c
Retain heterozygosity.