. Author manuscript; available in PMC: 2017 Dec 21.

Published in final edited form as: J Viral Hepat. 2016 Dec 1;24(5):380–388. doi: 10.1111/jvh.12656

TABLE 4.

The association between anti-HCV/HCV RNA status and all-cause mortality among 9117 NHANES III participants aged 18–59 years by race/ethnicity

	Anti-HCV negative	Anti-HCV positive (RNA positive and negative)		Anti-HCV and HCV RNA positive (chronic HCV)

		MRR (95% CI)^a	P-value	MRR (95% CI)^a	P-value
Non-Hispanic White

Total no. (N)	3169	60		44

All-cause mortality (n)	320	13		11

Age-and sex adjusted	1.00 [Reference]	3.52 (1.78–6.98)	.0003	4.52 (2.28–8.96)	<.001

Partially adjusted^b	1.00 [Reference]	2.30 (1.09–4.83)	.03	3.10 (1.53–6.29)	.002

Fully adjusted^c	1.00 [Reference]	2.04 (0.96–4.32)	.062	2.67 (1.28–5.56)	.009

Non-Hispanic Black

Total no. (N)	2668	104		92

All-cause mortality (n)	329	32		28

Age and sex adjusted	1.00 [Reference]	3.45 (2.12–5.62)	<.0001	3.38 (1.98–5.76)	<.001

Partially adjusted^b	1.00 [Reference]	2.63 (1.77–3.91)	<.0001	2.45 (1.58–3.81)	<.001

Fully adjusted^c	1.00 [Reference]	2.25 (1.39–3.63)	.001	2.02 (1.20–3.40)	.007

Mexican Americans

Total number (N)	2905	84		64

All-cause mortality (n)	206	24		21

Age and sex adjusted	1.00 [Reference]	4.25 (1.70–10.56)	.002	6.18 (2.52–15.14)	<.001

Partially adjusted^b	1.00 [Reference]	6.02 (2.22–16.30)	.0004	6.78 (2.20–20.90)	.001

Fully adjusted^c	1.00 [Reference]	6.22 (2.10–18.42)	.001	7.48 (2.15–26.10)	.002

Mortality rate ratio (95% confidence interval) versus anti-HCV negative.

Partial adjustment: demographics (age, sex, marital status, education, poverty income ratio), lifestyle (alcohol consumption, smoking status, lifetime cocaine and marijuana use, lifetime number of sexual partners), body mass index and comorbidities/viruses (cancer, diabetes, hepatitis A antibody, hepatitis E antibody).

Full adjustment factors: partial adjustment factors, liver function biomarkers (ALT, total bilirubin).