Table 1. NMR-based body composition.
IL 10tm 5 months Mean (SD) |
C57Bl/6 5 months Mean (SD) |
p-value | IL 10tm- 12 months Mean (SD) |
C57Bl/6 12 months Mean (SD) |
p-value | IL 10tm 22 months Mean (SD) |
C57Bl/6 22 months Mean (SD) |
p-value | |
---|---|---|---|---|---|---|---|---|---|
Body Weight | 24.15 (0.84) |
21.55 (0.20) |
0.0074 | 26.24 (0.84) |
30.36 (1.44) |
0.0283 | 29.68 (0.87) |
28.23 (1.06) |
0.3056 |
Lean Mass (%) | 60.42 (1.05) |
61.11 (0.73) |
0.1071 | 60.72 (2.04) |
59.66 (1.28) |
0.1863 | 62.72 (4.13) |
59.44 (1.94) |
0.0352 |
Fat Mass (%) | 15.87 (1.66) |
13.64 (0.81) |
0.0014 | 18.24 (3.43) |
21.36 (3.74) |
0.0765 | 13.9 (6.25) |
20.15 (1.17) |
0.0143 |
Fluid Mass (%) | 6.72 (0.29) |
6.95 (0.25) |
0.1133 | 6.95 (0.25) |
6.67 (0.30) |
0.0444 | 6.51 (0.26) |
6.88 (0.14) |
0.0008 |
NMR-based body composition from young, middle and old aged mice (n = 10 per group) at the time of indirect calorimetry testing. These values were used to normalize oxygen consumption measurements. SD = standard deviation.